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Fc gamma RIIA/CD32a Antibody (OTI9G5) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
OTI9G5
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70709AF350
Alexa Fluor 405
NBP2-70709AF405
Alexa Fluor 488
NBP2-70709AF488
Alexa Fluor 532
NBP2-70709AF532
Alexa Fluor 594
NBP2-70709AF594
Alexa Fluor 647
NBP2-70709AF647
Alexa Fluor 700
NBP2-70709AF700
Alexa Fluor 750
NBP2-70709AF750
Allophycocyanin
NBP2-70709APC
CoraFluor 1
NBP2-70709CL1
DyLight 350
NBP2-70709UV
DyLight 405
NBP2-70709V
DyLight 488
NBP2-70709G
DyLight 550
NBP2-70709R
DyLight 594
NBP2-70709DL594
DyLight 650
NBP2-70709C
DyLight 680
NBP2-70709FR
DyLight 755
NBP2-70709IR
FITC
NBP2-70709F
HRP
NBP2-70709H
Janelia Fluor 525
NBP2-70709JF525
Janelia Fluor 549
NBP2-70709JF549
Janelia Fluor 585
NBP2-70709JF585
Janelia Fluor 635
NBP2-70709JF635
Janelia Fluor 646
NBP2-70709JF646
Janelia Fluor 669
NBP2-70709JF669
PE
NBP2-70709PE
PerCP
NBP2-70709PCP
Unconjugated
NBP1-47735
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-47735
Azide and BSA Free
NBP2-70709
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Fc gamma RIIA/CD32a Antibody (OTI9G5) [Biotin] Summary

Immunogen
Full length recombinant protein of human Fc gamma RIIA/CD32a (NP_067674) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FCGR2A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Fc gamma RIIA/CD32a Antibody (OTI9G5) [Biotin]

  • CD32 antigen
  • CD32a
  • CD32MGC23887
  • CDw32fc-gamma-RIIa
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc gamma RIIA
  • FCG2
  • Fc-gamma RII-a
  • Fc-gamma-RIIa
  • FcGR
  • FCGR2
  • FCGR2A
  • FCGR2A1
  • FcgRIIA
  • FCRIIA
  • fcRII-a
  • IGFR2MGC30032
  • IgG Fc receptor II-a
  • Immunoglobulin G Fc receptor II
  • low affinity immunoglobulin gamma Fc region receptor II-a

Background

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Fc gamma
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NBP2-70709B
Fc gamma RIIA/CD32a Antibody (OTI9G5) [Biotin]
Species: Hu
Applications: WB, ICC/IF, IHC, IP

Publications for Fc gamma RIIA/CD32a Antibody (NBP2-70709B) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Fc gamma RIIA/CD32a Antibody (NBP2-70709B). (Showing 1 - 1 of 1 FAQ).

  1. Does any of your FCGR2A antibodies (19C10, 6D11, 13G9) cross react to FCGR2B?
    • For these antibodies, we have used the full-length protein FCGR2A (NP_067674) as the immunogen and we have not mapped the epitope that is detected with each Ab yet. I did an alignment of these two proteins and they are highly conserved thus it seems likely that there will be cross-reactivity.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol FCGR2A