Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA, Flow, ICC/IF, IP, B/N, Inhibition Activity
Host: Rabbit Monoclonal
Species: RM
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Bioactivity
Description
The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
2212 |
| Alternate Names |
- CD32 antigen
- CD32A
- CD32MGC23887
- CDw32fc-gamma-RIIa
- Fc fragment of IgG, low affinity IIa, receptor (CD32)
- Fc fragment of IgG, low affinity IIa, receptor for (CD32)
- FCG2
- Fc-gamma RII-a
- Fc-gamma-RIIa
- FcGR
- FCGR2
- FCGR2A1
- FcRII-a
- fcRII-a
- IGFR2MGC30032
- IgG Fc receptor II-a
- Immunoglobulin G Fc receptor II
- low affinity immunoglobulin gamma Fc region receptor II-a
|
![Sandwich ELISA Fc gamma RIIA/CD32a Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Fc-gamma-RIIA-CD32a-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79663-img0001.jpg)
![Binding Activity Fc gamma RIIA/CD32a [Unconjugated]](http://images.novusbio.com/fullsize2/Fc_gamma_RIIA_1330-CD_605.jpg)
![Binding Activity Fc gamma RIIA/CD32a [Unconjugated]](http://images.novusbio.com/fullsize2/Fc_gamma_RIIA_1330-CD_CF_606.jpg)
![Bioactivity Fc gamma RIIA/CD32a [Unconjugated]](http://images.novusbio.com/fullsize2/Fc_gamma_RIIA_9595CD_1662.jpg)
![SDS-PAGE Fc gamma RIIA/CD32a [Unconjugated]](http://images.novusbio.com/fullsize2/Fc_gamma_RIIA_1330-CD_601.jpg)
![SDS-PAGE Fc gamma RIIA/CD32a [Unconjugated]](http://images.novusbio.com/fullsize2/Fc_gamma_RIIA_1330-CD_CF_604.jpg)