Species: Hu
Applications: WB, ICC/IF, IHC, IP, KD
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
57697 |
| Alternate Names |
- ATP-dependent RNA helicase FANCM
- EC 3.6.1
- FAAP250EC 3.6.4.13
- Fanconi anemia, complementation group M
- Fanconi anemia-associated polypeptide of 250 kDa
- KIAA1596Fanconi anemia group M protein
- MGC176453
- Protein FACM
- Protein Hef ortholog
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Related FANCM Blog Posts
Check out the latest blog posts on FANCM.
Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)... Read more.
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Read more FANCM related blogs.
