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FANCE Antibody

Images

 
Analysis in human cell line RT-4.
Staining of human cell line THP-1 shows localization to nucleoplasm, mitotic chromosome & centrosome.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

FANCE Antibody Summary

Immunogen
This antibody has been engineered to specifically recognize the recombinant protein FANCE using the following amino acid sequence: SGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FANCE
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 µg/ml
  • Western Blot 0.04-0.4 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for FANCE Antibody

  • FACEFAE
  • Fanconi anemia group E protein
  • Fanconi anemia, complementation group E
  • Protein FACE

Background

FANCE (Fanconi anemia, complementation group E) is a protein involved in DNA repair. Defects in FANCE are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCE gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. FANCE has been shown to mediate the interaction between FANCC and FANCD2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for FANCE Antibody (NBP3-24840) (0)

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Secondary Antibodies

 

Isotype Controls

Additional FANCE Products

Array NBP3-24840

Research Areas for FANCE Antibody (NBP3-24840)

Find related products by research area.

Blogs on FANCE.

Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)...  Read full blog post.

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Bioinformatics

Gene Symbol FANCE