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Endoglin/CD105 Antibody Pair [HRP]

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Sandwich ELISA: Endoglin/CD105 Antibody Pair [HRP] [NBP2-79580] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
31.25-2000 pg/ml (example only; lot dependent)
Sensitivity
31.25 pg/ml (example only; lot dependent)

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Catalog# & Conjugate Size Price
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Endoglin/CD105 Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Mouse Endoglin/CD105.
Additional Information
Recombinant Monoclonal Antibody
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Mouse Endoglin/CD105.
Standard Curve Range
31.25-2000 pg/ml (example only; lot dependent)
Sensitivity
31.25 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
ENG

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Standard

Alternate Names for Endoglin/CD105 Antibody Pair [HRP]

  • CD105 antigen
  • CD105
  • Endoglin
  • ENDOsler-Rendu-Weber syndrome 1
  • ENG
  • HHT1FLJ41744
  • ORW
  • ORW1

Background

CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Product General Protocols

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FAQs for Endoglin/CD105 Antibody Pair (NBP2-79580). (Showing 1 - 2 of 2 FAQ).

  1. I wonder if you have a CD105 or CD34 antibody suitable for IHC that is specific for human and do not bind mouse?
    • We do not have any anti-human CD34 or CD105 antibodies that are confirmed to NOT detect the mouse protein. When we have tested an antibody and confirmed that it will not react with mouse samples, we will add Mu(-) to the datasheet, and unfortunately all of our CD105 and CD34 antibodies will either detect the mouse protein, or they have not been used in mouse samples before.
  2. We are interested in CD105 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
    • We do not currently carry any CD105 antibodies that have been validated for use in dog samples. However, if you are interested in testing any of our CD105 antibodies with dog samples you would be eligible for our Innovators Reward Program, in which you can get a discount voucher for the purchase price of the product. Please contact us at innovators@novusbio.com with any questions regarding this program.

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Bioinformatics

Gene Symbol ENG