EBI3 Antibody (15k8D10) - Azide Free

Interleukin-35 is a novel heterodimeric cytokine composed of the IL-12p35 subunit and the Epstein-Barr virus-induced gene 3 (EBI3) protein. As one of the IL-12 family members, Interleukin-35 is known to play an essential role in immune regulation of the CD4+CD25+ regulatory T (Treg) cells, from which Interleukin-35 is also specifically produced. Interleukin-35 is able to expand CD4+CD25+ Treg cells whereas it can inhibit proliferation of CD4+CD25- effector T (Teff) cells and development of proinflammatory Th17 cells, suppressing inflammatory responses.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 2 of 2.

Publications using NBP2-27363	Applications	Species
Mao H, Gao W, Ma C et al. Human placental trophoblasts express the immunosuppressive cytokine IL-35. Hum Immunol. 2013-07-01 [PMID: 23619469] (IHC-P, Human) Details: IHC (P), Fig 1: first-trimester human placentae.	IHC-P	Human
Wang Z, Liu JQ, Liu Z et al. Tumor-derived IL-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis. J Immunol. 2013-03-01 [PMID: 23345334] (IHC-P, Human) Details: IHC (P), Fig 1: human large B cell lymphoma, nasopharyngeal carcinoma, skin, melanoma, lymph node metastatic melanoma.	IHC-P	Human

Array NBP2-27363

• EBI3 Antibodies
• EBI3 Lysate
• EBI3 Proteins
• EBI3 Proteins and Enzyme
• EBI3 ELISA