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EBI3 Antibody (15k8D10) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
15k8D10
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-27362AF350
Alexa Fluor 405
NBP2-27363AF405
Alexa Fluor 488
NBP2-27363AF488
Alexa Fluor 532
NBP2-27362AF532
Alexa Fluor 594
NBP2-27362AF594
Alexa Fluor 647
NBP2-27363AF647
Alexa Fluor 700
NBP2-27363AF700
Alexa Fluor 750
NBP2-27362AF750
Biotin
NBP2-27363B
DyLight 350
NBP2-27363UV
DyLight 405
NBP2-27363V
DyLight 488
NBP2-27363G
DyLight 550
NBP2-27363R
DyLight 594
NBP2-27362DL594
DyLight 650
NBP2-27363C
DyLight 680
NBP2-27363FR
DyLight 755
NBP2-27363IR
FITC
NBP2-27363F
Janelia Fluor 549
NBP2-27362JF549
Janelia Fluor 646
NBP2-27362JF646
Unconjugated
NBP2-27362
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-27362
BSA Free
NBP2-27362
Azide Free
NBP2-27363
BSA Free
NBP2-27362SS
Azide Free
NBP2-27363-0.5mg
Azide Free
NBP2-27363-1mg
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EBI3 Antibody (15k8D10) [HRP] Summary

Immunogen
A full-length human Interleukin-35-Fc fusion protein was used as immunogen for this antibody.
Specificity
The human Interleukin-35 protein is a dimeric protein consisting of the human IL-12a/p35 subunit (NP_000873.2) and the human EBI3 (NP_005746) protein. Clone 15K8D10 tests as being specific to the EBI3 subunit of the target protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EBI3
Purity
Protein G purified
Endotoxin Note
< 0.06 EU/ug
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for EBI3 Antibody (15k8D10) [HRP]

  • cytokine receptor
  • EBI3
  • EBI-3
  • EBV-induced gene 3 protein
  • Epstein-Barr virus induced 3
  • Epstein-Barr virus induced gene 3
  • Epstein-Barr virus-induced gene 3 protein
  • IL-27 beta
  • IL-27 subunit beta
  • IL27B
  • IL-27B
  • IL35 EBI3
  • IL-35 EBI3
  • interleukin-27 subunit beta

Background

EBI3 gene encodes a 229 amino acid long, 25 kDA interleukin-27 subunit beta protein that is member to the hematopoitetin receptor family. These proteins obtain pro as well as anti-inflammatory properties and have roles in T-helper cell development, suppressing cell proliferation, encouraging cytotoxic T-cell activity, and can induce isotope switching in B cells. EBI3 participates in Th1 differentiation, IL-2 signaling (and its primary biological effects in various immune cells), as well as IL27-mediated signaling events. EBI3 interacts with genes IL27, IL12A, CANX, MDF1, and SMAD3. It has been associated and researched in sepsis, asthma, carcinoma, Chron's disease, b-cell lymphomas, ulcerative colitis, Hodgkin disease, lymphoma, ebv infections, and glomerulonephritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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EBI3 Antibody
(15k8D10) [HRP]
NBP2-27363H
EBI3 Antibody (15k8D10) [HRP]
Species: Hu
Applications: WB, IHC
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EBI3