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Dnd1 Antibody

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Staining of human cell line HAP1 shows localization to nucleoplasm.
Staining of human cell line HAP1 shows localization to nucleoplasm.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Dnd1 Antibody Summary

Immunogen
This antibody has been engineered to specifically recognize the recombinant protein Dnd1 using the following amino acid sequence: MMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTEKCELSVDGLPPNLTRSALLLALQPLGPGLQE
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DND1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Dnd1 Antibody

  • dead end homolog 1 (zebrafish)
  • dead end protein homolog 1
  • RBMS4MGC34750
  • RNA-binding motif, single-stranded-interacting protein 4

Background

RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression.Relieves miRNA repression in germline cells . Prohibits the function of several miRNAs by blocking theaccessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs)in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordialgerm cell (PGC) survival . However, does not seem to be essential for PGC migration

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DND1