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Derlin-2 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485] - Staining in human thyroid gland and skeletal muscle tissues using anti-DERL2 antibody. Corresponding DERL2 RNA-seq data are ...read more
Western Blot: Derlin-2 Antibody [NBP2-47485] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line U-251 MG.
Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Derlin-2 Antibody [NBP2-47485] - Staining of human thyroid gland shows high expression.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Derlin-2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: NYNPLPEERPGGFAWGEGQRLGG
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DERL2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Derlin-2 Protein (NBP2-47485PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Derlin-2 Antibody

  • carcinoma related
  • Degradation in endoplasmic reticulum protein 2
  • Der1-like domain family, member 2
  • Der1-like protein 2
  • DER2
  • derlin-2
  • F-LAN-1DERtrin-2
  • FLANa
  • F-LANaCGI-101

Background

DERL2 (Derlin 2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol DERL2