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Defensin alpha 5 Antibody (8C8) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, DB, ELISA, Flow, ICC/IF, IHC
Clone
8C8
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-60002AF350
Alexa Fluor 405
NB110-60002AF405
Alexa Fluor 488
NB110-60002AF488
Alexa Fluor 532
NB110-60002AF532
Alexa Fluor 594
NB110-60002AF594
Alexa Fluor 647
NB110-60002AF647
Alexa Fluor 700
NB110-60002AF700
Alexa Fluor 750
NB110-60002AF750
Allophycocyanin
NB110-60002APC
Biotin
NB110-60002B
DyLight 350
NB110-60002UV
DyLight 405
NB110-60002V
DyLight 488
NB110-60002G
DyLight 550
NB110-60002R
DyLight 594
NB110-60002DL594
DyLight 650
NB110-60002C
DyLight 680
NB110-60002FR
DyLight 755
NB110-60002IR
FITC
NB110-60002F
HRP
NB110-60002H
Janelia Fluor 646
NB110-60002JF646
PE
NB110-60002PE
Unconjugated
NB110-60002
mFluor Violet 450 SE
NB110-60002MFV450
mFluor Violet 500 SE
NB110-60002MFV500
mFluor Violet 610 SE
NB110-60002MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-60002
Azide and BSA Free
NBP2-80693
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Defensin alpha 5 Antibody (8C8) [Janelia Fluor® 549] Summary

Immunogen
Full-length human Defensin alpha 5 [Swiss-Prot# Q01523]. The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).
Localization
Secreted protein.
Specificity
This is specific for HD5. It does not cross-react with HD6, lysozyme or sPLA2.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
DEFA5
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Dot Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Defensin alpha 5 Antibody (8C8) [Janelia Fluor® 549]

  • alpha-Defensin 5
  • DEF5
  • DEF5defensin, alpha 5, preproprotein
  • DEFA5
  • defensin 5
  • Defensin alpha 5
  • Defensin, alpha 5
  • defensin, alpha 5, Paneth cell-specific
  • defensin-5
  • HD-5
  • MGC129728

Background

Defensin alpha 5 (DEFA5) is primarily responsible for host defense. DEFA5 has shown antimicrobial activity and is thought to kill microbes by permeabilizing their plasma membrane. This protein is highly expressed in the secretory granules of Paneth cells of the ileum.

Defensin alpha 5 antibodies are useful tools for bacterial defense studies and human immunology research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Defensin alpha 5
Antibody (8C8) [Janel ...
NB110-60002JF549
Defensin alpha 5 Antibody (8C8) [Janelia Fluor® 549]
Species: Hu
Applications: WB, DB, ELISA, Flow, ICC/IF, IHC

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Product General Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DEFA5