DDX41 Antibody (2F4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 6 of 6.

Publications using H00051428-M01	Applications	Species
Kim JA, Shen S, Matson DR et al. Discriminating activities of DEAD-Box Helicase 41 from myeloid malignancy-associated germline variants by genetic rescue Leukemia 2022-11-08 [PMID: 36347925] (WB, Human)	WB	Human
Yoneyama-Hirozane M, Kondo M, Matsumoto SI et al. High-Throughput Screening to Identify Inhibitors of DEAD Box Helicase DDX41. SLAS Discov 2017-04-01 [PMID: 28426938]
Omura H, Oikawa D, Nakane T et al. Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. Sci Rep 2016-10-10 [PMID: 27721487]
Ma F, Li B, Liu SY et al. Positive Feedback Regulation of Type I IFN Production by the IFN-Inducible DNA Sensor cGAS J. Immunol. 2015-01-21 [PMID: 25609843] (WB)	WB
Parvatiyar K, Zhang Z, Teles RM et al. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response Nat Immunol 2012-12-01 [PMID: 23142775] (WB, ICC/IF, Mouse)	WB, ICC/IF	Mouse
Zhang Z, Yuan B, Bao M et al. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nature Immunology. 2011-09-04 [PMID: 21892174]

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	WB	Human	02/11/2015	View Summary Application Western Blot Sample Tested HEK CELL LYSATE Species Human

Array H00051428-M01

• DDX41 Antibodies
• DDX41 Lysate
• DDX41 Proteins