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Cytochrome C Oxidase subunit 6c Antibody (S51)

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Immunohistochemistry-Paraffin: Cytochrome C Oxidase subunit 6c Antibody (S51) [H00001345-M03] - Analysis of monoclonal antibody to COX6C on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration ...read more
ELISA: Cytochrome C Oxidase subunit 6c Antibody (S51) [H00001345-M03] - Detection limit for recombinant GST tagged COX6C is approximately 1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
S51
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Cytochrome C Oxidase subunit 6c Antibody (S51) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
COX6C (AAH00187, 1 a.a. ~ 75 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAPEVLPKPRMRGLLARRLRNHMAVAFVLSLGVAALYKFRVADQRKKAYADFYRNYDVMKDFEEMRKAGIFQSVK
Specificity
COX6C - cytochrome c oxidase subunit VIc
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
COX6C
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytochrome C Oxidase subunit 6c Antibody (S51)

  • Cytochrome c oxidase polypeptide VIc
  • cytochrome c oxidase subunit 6C
  • cytochrome c oxidase subunit VIc preprotein
  • cytochrome c oxidase subunit VIc

Background

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse COX subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene COX6CP1 has been found on chromosomes 16p12.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol COX6C
Entrez
OMIM
Uniprot