CXCL8/IL-8 Antibody

IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human,  Human.

We have publications tested in 3 applications: IHC, IHC-P, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP2-33819	Applications	Species
Li L, Yao W, Yan S Et al. Pan-Cancer Analysis of Prognostic and Immune Infiltrates for CXCs Cancers 2021-08-18 [PMID: 34439306] (IHC-P, Human)	IHC-P	Human
C Owen-Woods, R Joulia, A Barkaway, L Rolas, B Ma, AF Nottebaum, KP Arkill, M Stein, T Girbl, M Golding, DO Bates, D Vestweber, MB Voisin, S Nourshargh Local microvascular leakage promotes trafficking of activated neutrophils to remote organs J. Clin. Invest., 2020-05-01;0(0):. 2020-05-01 [PMID: 31971917] (IHC, Human)	IHC	Human
Fronczek J, Lulf R, Korkmaz Hi, Witte Bi. Analysis of inflammatory cells and mediators in skin wound biopsies to determine wound age in living subjects in forensic medicine Forensic Science International et al. 2014-11-22 [PMID: 25506669] (IHC-P, Human) Details: CXCL8/IL-8 antibody used at 1:100 dilution in IHC-P application on human tissues from skin wounds in living subjects in forensic medicine - 4% formaldehyde solution fixation, 4um paraffin sections, endogenous peroxidases blocking with methanol/H2O2 (0.3%) for 30 min, antigen retrieval via boiling of slides for 10 min in Tris-EDTA pH 9, primary incubation for 1 h at room temperature, detection with rabbit Envision - DAB (Fig. 1e and 1f)	IHC-P	Human
Yu S, Chung S, Ha H et al. Nanotheranostics of Pre Stenotic Vessels By Target Touch On Signaling of Peptide Navigator Advanced Functional Materials 2021-12-08 (WB)	WB

Array NBP2-33819

• CXCL8/IL-8 Antibodies
• CXCL8/IL-8 Antibody Pair
• CXCL8/IL-8 ELISA Kits
• CXCL8/IL-8 Kits
• CXCL8/IL-8 Lysate
• CXCL8/IL-8 Proteins
• CXCL8/IL-8 ELISAs
• CXCL8/IL-8 Proteins and Enzymes