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csl/RBPJK Antibody (4E12)

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Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01] - Analysis of RBPJ expression in transfected 293T cell line by RBPJ monoclonal antibody (M01), clone 4E12.Lane 1: RBPJ transfected lysate(54.3 KDa).Lane 2: Non-transfected lysate.
Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01] - Analysis of RBPJ expression in transfected 293T cell line by RBPJ monoclonal antibody (M01), clone 4E12.Lane 1: RBPJ transfected lysate(54.3 KDa).Lane 2: ...read more
Western Blot: csl/RBPJK Antibody (4E12) [H00003516-M01] - RBPJ monoclonal antibody (M01), clone 4E12 Analysis of RBPJ expression in Jurkat.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4E12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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csl/RBPJK Antibody (4E12) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
RBPJ (NP_976029, 3 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. WIKRKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYC
Specificity
recombining binding protein suppressor of hairless (Drosophila)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RBPJ
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for csl/RBPJK Antibody (4E12)

  • CBF1
  • CBF-1
  • CSL
  • H-2K binding factor-2
  • IGKJRB1
  • IGKJRB1RBPSUHCBF1
  • IGKJRBRBP-J kappa
  • immunoglobulin kappa J region recombination signal binding protein 1
  • J kappa-recombination signal-binding protein
  • KBF2
  • RBPJ
  • RBP-JK
  • RBPJKMGC61669
  • RBP-Jrecombining binding protein suppressor of hairless (Drosophila)
  • RBPSUH
  • recombination signal binding protein for immunoglobulin kappa J region
  • recombining binding protein suppressor of hairless
  • Renal carcinoma antigen NY-REN-30
  • SUH
  • suppressor of hairless homolog

Background

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RBPJ
Entrez
OMIM
Uniprot