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HES5 Antibody

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Western Blot: HES5 Antibody [NBP2-27174] - analysis of HES5 in mouse liver tissue lysate in the 1) absence and 2) presence of immunizing peptide using HES5 antibody at 7 ug/ml. goat anti-rabbit Ig HRP secondary antibody ...read more
Immunohistochemistry-Paraffin: HES5 Antibody [NBP2-27174] - analysis of HES5 in formalin-fixed, paraffin-embedded human brain tissue using HES5 antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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HES5 Antibody Summary

Immunogen
A portion of amino acid1-50 of human HES5 was used as the immunogen for this antibody.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HES5
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5ug/ml
  • Western Blot 6-9ug/ml~

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for HES5 Antibody

  • BHLHB38
  • bHLHb38Class B basic helix-loop-helix protein 38
  • hairy and enhancer of split 5 (Drosophila)
  • Hairy and enhancer of split 5
  • transcription factor HES-5

Background

Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional HES5 Products

Array NBP2-27174

Research Areas for HES5 Antibody (NBP2-27174)

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Bioinformatics

Gene Symbol HES5
Uniprot