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CSB Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: CSB Antibody [NBP2-68917] - Staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear bodies. Antibody staining is shown in green.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CSB Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: TLSLHEITDLLETDDSIEASAIVIQPPENATAPVSDEESGDEEGGTINNLPGSLLHTAAYLIQDGSDAESDSDDPSYAPKDDSPDEVPSTFTVQQPPPSRRRKMTKILCKWKKADLTVQPVAGRVTAPPNDFFTVMRTPTE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERCC6
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Recommended conditions: Fixation/Permeabilization: PFA/Triton X-100
Control Peptide
CSB Recombinant Protein Antigen (NBP2-68917PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for CSB Antibody

  • ARMD5
  • ATP-dependent helicase ERCC6
  • CKN2
  • Cockayne syndrome group B protein
  • Cockayne syndrome protein CSB
  • COFS
  • COFS1
  • CSBCockayne syndrome B protein
  • DNA excision repair protein ERCC-6
  • EC 3.6.1
  • EC 3.6.4.-
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 6
  • Rad26 homolog
  • RAD26

Background

ERCC6, also known as Cockayne syndrome B protein, is involved in DNA repair in response to UV exposure. ERCC6 has been reported to display ATPase and helicase activity and functions as a transcriptional regulator. Mutations in ERCC6 are the cause of Cockayne syndrome type B (CSB), cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DCS), age-related macular degeneration type 5 (ARMD5), and UV-sensitive syndrome (UVS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for CSB Antibody (NBP2-68917) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ERCC6