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Connexin 43/GJA1 Antibody

Images

 
Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] - Western blot analysis using a Connexin 43 polyclonal antibody (Product # NBP3-24691) in CEM cell lysates (35 ug per lane).
Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP3-24691] - Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cancer tissue using a Connexin 43 polyclonal antibody (Product # ...read more
Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] - Western blot analysis using a Connexin 43 polyclonal antibody (Product # NBP3-24691) in mouse brain tissue lysates (35 ug per lane).

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Connexin 43/GJA1 Antibody Summary

Immunogen
KLH conjugated synthetic peptide between 107-138 amino acids from the N-terminal region of human Connexin 43/GJA1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GJA1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100
  • Western Blot 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Purity
Protein G purified

Alternate Names for Connexin 43/GJA1 Antibody

  • Connexin 43
  • connexin-43
  • CX43
  • CX43gap junction protein, alpha-like
  • DFNB38
  • Gap junction 43 kDa heart protein
  • gap junction alpha-1 protein
  • gap junction protein, alpha 1, 43kDa (connexin 43)
  • gap junction protein, alpha 1, 43kDa
  • GJA1
  • GJAL
  • HSS
  • ODD
  • ODDD
  • ODOD
  • SDTY3

Background

Connexin 43/GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major cardiac gap junction protein, which is thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Connexin 43/GJA1 Antibody (NBP3-24691) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on Connexin 43/GJA1.

Connexin: Bridging the Gap of Intercellular Communication
Connexin 43/GJA1 is a member of the connexin gene family and the most abundant protein component found within gap junctions. Gap junctions are the cell-to-cell contacts that provide direct intercellular communication between cells by regulating back a...  Read full blog post.

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Bioinformatics

Gene Symbol GJA1