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Complement Factor I Antibody (OTI7C9)

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Western Blot: Complement Factor I Antibody (7C9) [NBP2-46264] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Complement Factor 1.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI7C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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Complement Factor I Antibody (OTI7C9) Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 340-583 of human CFI(NP_000195) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CFI
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin
  • Western Blot 1:2000
Theoretical MW
63.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Complement Factor I Antibody (OTI7C9)

  • AHUS3
  • C3b Inactivator
  • C3B/C4B inactivator
  • C3BINA
  • C3b-inactivator
  • CFI
  • complement component I
  • complement control protein factor I
  • complement factor I heavy chain
  • Complement Factor I
  • EC 3.4.21
  • EC 3.4.21.45
  • FIC3b-INA
  • I factor (complement)
  • IF
  • KAF
  • Konglutinogen-activating factor
  • light chain of factor I

Background

Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CFI