![Immunohistochemistry-Paraffin: Complement C3d Antibody (053A-1149.3.1.4) [NB100-65510] - Immunohistochemistry staining for C3d in human renal biopsy. IHC-P image submitted by a verified customer review.](http://images.novusbio.com/fullsize/Complement-C3d-Antibody-053A-1149-3-1-4-Immunohistochemistry-Paraffin-NB100-65510-img0001.jpg "Immunohistochemistry-Paraffin: Complement C3d Antibody (053A-1149.3.1.4) [NB100-65510] - Immunohistochemistry staining for C3d in human renal biopsy. IHC-P image submitted by a verified customer review.")
| Reactivity | HuSpecies Glossary |
| Applications | WB, ELISA, Flow, IHC |
| Clone | 053A-1149.3.1.4 (1003) |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Immunogen | Purified C3d from human plasma |
| Specificity | NB100-65510 is specific for human complement component 3d (C3d), a 33kDa polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | C3 |
| Purity | Protein A purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Reviewed Applications |
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| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | Borate buffered saline (pH 8.4) |
| Preservative | 0.1% Sodium Azide |
| Purity | Protein A purified |
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| Images | Ratings | Applications | Species | Date | Details | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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reviewed by:
Verified Customer |
IHC-Fr | Human | 08/05/2021 |
Summary
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Secondary Antibodies |
Isotype Controls |
Research Areas for Complement C3d Antibody (NB100-65510)Find related products by research area.
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