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CDT2 Antibody

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Immunocytochemistry/ Immunofluorescence: CDT2 Antibody [NBP2-58215] - Staining of human cell line U-251 MG shows localization to nucleus, nucleoli & cytosol.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CDT2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DTL
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
CDT2 Recombinant Protein Antigen (NBP2-58215PEP)

Reactivity Notes

Mouse 88%, Rat 87%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CDT2 Antibody

  • CDT2RA-regulated nuclear matrix-associated protein
  • CDW1
  • DCAF2DDB1 and CUL4 associated factor 2
  • DDB1- and CUL4-associated factor 2
  • denticleless homolog (Drosophila)
  • L2DTLRA regulated nuclear matrix associated protein
  • Lethal(2) denticleless protein homolog
  • RAMPdenticleless protein homolog
  • Retinoic acid-regulated nuclear matrix-associated protein

Background

DTL promotes genomic stability through two distinct mechanisms. First, it is an essential component of the CUL4-DDB1 complex that controls CDT1 levels, thereby preventing rereplication. Second, it is required for the early G2/M checkpoint.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for CDT2 Antibody (NBP2-58215) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DTL