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CDT2 Antibody

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Immunohistochemistry-Paraffin: CDT2 Antibody [NBP1-85283] - Staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CDT2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIF
Predicted Species
Mouse (97%), Rat (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DTL
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
CDT2 Protein (NBP1-85283PEP)
Publications
Read Publication using NBP1-85283.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for CDT2 Antibody

  • CDT2RA-regulated nuclear matrix-associated protein
  • CDW1
  • DCAF2DDB1 and CUL4 associated factor 2
  • DDB1- and CUL4-associated factor 2
  • denticleless homolog (Drosophila)
  • L2DTLRA regulated nuclear matrix associated protein
  • Lethal(2) denticleless protein homolog
  • RAMPdenticleless protein homolog
  • Retinoic acid-regulated nuclear matrix-associated protein

Background

DTL promotes genomic stability through two distinct mechanisms. First, it is an essential component of the CUL4-DDB1 complex that controls CDT1 levels, thereby preventing rereplication. Second, it is required for the early G2/M checkpoint.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CDT2 Antibody (NBP1-85283)(1)


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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DTL