Western Blot: CDT2 Antibody [NB100-40840] - Whole cell lysate (15 ug) from Jurkat, HeLa, and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DTL/CDT2 antibody used for WB at 0.04 ...read more
Immunohistochemistry-Paraffin: CDT2 Antibody [NB100-40840] - Section of mouse plasmacytoma. Antibody: Affinity purified rabbit anti-DTL/CDT2 used at a dilution of 1:200 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: CDT2 Antibody [NB100-40840] - Section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-DTL/CDT2 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB
Immunoprecipitation: CDT2 Antibody [NB100-40840] - Detection of human DTL/CDT2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from Jurkat cells prepared ...read more
The immunogen recognized by this antibody maps to a region between residue 680 and the C-terminus (residue 730) of human Denticleless Homolog (Chromatin Licensing and DNA Replicating Factor 2) using the numbering given in entry NP_057532.1 (GeneID 51514)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DTL
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
CDT2RA-regulated nuclear matrix-associated protein
CDW1
DCAF2DDB1 and CUL4 associated factor 2
DDB1- and CUL4-associated factor 2
denticleless homolog (Drosophila)
L2DTLRA regulated nuclear matrix associated protein
Lethal(2) denticleless protein homolog
RAMPdenticleless protein homolog
Retinoic acid-regulated nuclear matrix-associated protein
Background
DTL promotes genomic stability through two distinct mechanisms. First, it is an essential component of the CUL4-DDB1 complex that controls CDT1 levels, thereby preventing rereplication. Second, it is required for the early G2/M checkpoint.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
We have publications tested in 1 confirmed species: Human.
We have publications tested in 3 applications: IF, IP, WB.
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Showing Publications 1 - 7 of 7.
Publications using NB100-40840
Applications
Species
Renna F, Steinberg J, Manifava M et al. Ubiquitination is a novel post-translational modification of VMP1 in autophagy of human tumor cells bioRxiv 2023-02-14 (IF)
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