RAMP2 Antibody (773816) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

RAMP2 (receptor activity modifying protein 2) is a 20 kDa member of the RAMP family of proteins. It is expressed on cardiomyocytes, vascular smooth muscle cells and endothelium and interacts with CRLR to form a receptor complex for adrenomedullin (AM). AM induces vasodilation on AM1 receptor expressing cells. Mature mouse RAMP2 is a 145 amino acid (aa) type I transmembrane glycoprotein that contains a 115 aa extracellular domain (ECD) (aa 45-159) and a nine aa cytoplasmic region. Although the ECD contains no typical structural motifs, based on human, aa 100-106 are critical for AM binding. Over aa 45-159, mouse RAMP2 shares 57% and 83% aa identity with human and rat RAMP2, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC.

Showing Publication 1 - 1 of 1.

Publication using MAB6500	Applications	Species
Iwata, S;Yoshida, R;Takai, S;Sanematsu, K;Shigemura, N;Ninomiya, Y; Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway Nutrients 2023-01-01 [PMID: 37447268] (IHC, Mouse)	IHC	Mouse

Array MAB6500

• RAMP2 Antibodies
• RAMP2 Lysate
• RAMP2 Proteins