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CD94 Antibody (131412) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
131412
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

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CD94 Antibody (131412) [DyLight 550] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human CD94 and NKG2A
Specificity
Recognizes human CD94 both in its homodimeric form and as a heterodimer with either NKG2A or NKG2C.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KLRD1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD94 Antibody (131412) [DyLight 550]

  • CD94 antigen
  • CD94
  • CD94natural killer cells antigen CD94
  • Killer cell lectin-like receptor subfamily D member 1
  • killer cell lectin-like receptor subfamily D, member 1
  • KLRD1
  • KP43
  • NK cell receptor

Background

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. KLRD1 has two alternatively spliced variants that differ in the presence or absence of exon 2 sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CD94 Antibody (FAB1058L) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KLRD1