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CD58/LFA-3 Antibody (186) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
186
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 405

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CD58/LFA-3 Antibody (186) [Alexa Fluor® 405] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD58/LFA-3 (Accession#: AAH05930.1; Met1-Arg215).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CD58
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD58/LFA-3 Antibody (186) [Alexa Fluor® 405]

  • Ag3
  • CD58 antigen
  • CD58 antigen, (lymphocyte function-associated antigen 3)
  • CD58 molecule
  • CD58
  • FLJ23181
  • FLJ43722
  • LFA3
  • LFA-3
  • LFA3ag3
  • lymphocyte function-associated antigen 3
  • Surface glycoprotein LFA-3

Background

LFA3 is a type 1 transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on most hematopoietic cells and on nonhematopoietic cells such as fibroblasts, endothelial and epithelial cells. Its expression is particularly high on memory T-cells and dendritic cells. LFA3 expression on antigen-presenting cells and target cells enhances T-cells antigen recognition through binding to its ligand, LFA2/CD2, on T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD58