Orthogonal Strategies: Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Analysis in human lung and prostate tissues using NBP1-85466 antibody. Corresponding CD55 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining of human lung shows strong membranous positivity in pneumocytes.
Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining of human placenta shows strong membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining of human tonsil shows moderate membranous positivity in germinal center cells.
Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining of human prostate shows no positivity in glandular cells as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISF
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CD55
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Feline reactivity reported in scientific literature (PMID: 25671605). Use in Mouse reported in scientific literature (PMID:32142650).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for CD55/DAF Antibody
CD55 antigen
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD55
CR
CRdecay accelerating factor for complement (CD55, Cromer blood group system)
CROMDAFcomplement decay-accelerating factor
DAF
decay accelerating factor for complement
TC
Background
CD55 encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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