CD300f/LMIR3/CD300LF Antibody

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Mouse CD300f, also known as LMIR3, CLM-1, IgSF13, IREM-1 and CMRF35-like molecule 1, is a 55 kDa type I transmembrane (TM) glycoprotein. It is synthesized as a 283 amino acid (aa) precursor that contains a putative 19 aa signal sequence, a 175 aa extracellular region that contains one Ig-like domain, a 17 aa TM segment and a 72 aa cytoplasmic domain that contains an ITIM sequence. There are multiple alleles for this gene that vary considerably in size. Mouse LMIR3 is expressed in monocytic cell lines. Mature mouse LMIR3 extracellular region shares 43% and 72% aa identity with human and rat LMIR3 extracellular region, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: Functional Assay, Immunoprecipitation, Western Blot.

Showing Publications 1 - 7 of 7.

Publications using AF2788	Applications	Species
Emily W. Helm, Amy M. Peiper, Matthew Phillips, Caroline G. Williams, Michael B. Sherman, Theresa Kelley et al. Environmentally-triggered contraction of the norovirus virion determines diarrheagenic potential Frontiers in Immunology 11/1/2022 [PMID: 36389732]
DJ Hayman, T Modebadze, S Charlton, K Cheung, J Soul, H Lin, Y Hao, CG Miles, D Tsompani, RM Jackson, MD Briggs, KA Piróg, IM Clark, MJ Barter, GJ Clowry, FEN LeBeau, DA Young Increased hippocampal excitability in miR-324-null mice Scientific Reports, 2021-05-17;11(1):10452. 2021-05-17 [PMID: 34001919] (Western Blot, Mouse)	Western Blot	Mouse
Kevin Furlong, Scott B. Biering, Jayoung Choi, Craig B. Wilen, Robert C. Orchard, Christiane E. Wobus et al. CD300LF Polymorphisms of Inbred Mouse Strains Confer Resistance to Murine Norovirus Infection in a Cell Type-Dependent Manner Journal of Virology 8/17/2020 [PMID: 32581099]
K Ueno, M Urai, K Izawa, Y Otani, N Yanagihara, M Kataoka, S Takatsuka, M Abe, H Hasegawa, K Shimizu, T Kitamura, J Kitaura, Y Miyazaki, Y Kinjo Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils Sci Rep, 2018-11-27;8(1):17406. 2018-11-27 [PMID: 30479367] (Western Blot, Mouse)	Western Blot	Mouse
KR Grau, AN Roth, S Zhu, A Hernandez, N Colliou, BB DiVita, DT Philip, C Riffe, B Giasson, SM Wallet, M Mohamadzad, SM Karst The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue Nat Microbiol, 2017-11-06;0(0):. 11/6/2017 [PMID: 29109476]
Kei Haga, Akira Fujimoto, Reiko Takai-Todaka, Motohiro Miki, Yen Hai Doan, Kosuke Murakami et al. Functional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells Proceedings of the National Academy of Sciences 10/11/2016 [PMID: 27681626]
Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Kaitani A, Sugiuchi M, Takahashi M, Maehara A, Enomoto Y, Oki T, Takai T, Kitamura T An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells. J. Immunol., 2009-06-26;183(2):925-36. 2009-06-26 [PMID: 19561101] (Functional Assay, Immunoprecipitation, Western Blot, Mouse)	Functional Assay, Immunoprecipitation, Western Blot	Mouse

Array AF2788

• CD300f/LMIR3/CD300LF Antibodies
• CD300f/LMIR3/CD300LF ELISA Kits
• CD300f/LMIR3/CD300LF Lysate
• CD300f/LMIR3/CD300LF Protein
• CD300f/LMIR3/CD300LF Proteins and Enzymes