![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) Pacific BlueTM.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0010.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) Pacific BlueTM.")
| Reactivity | Hu, PmSpecies Glossary |
| Applications | Flow, IHC, IP, CyTOF-ready |
| Clone | BU15 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Format | BSA Free |
| Concentration | 1 mg/ml |
| Additional Information | Clone BU15 was used by HLDA to establish CD designation. |
| Immunogen | Dendritic cells of synovial fluid |
| Marker | Dendritic Cell Marker |
| Specificity | The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages. HLDA III; WS Code M 256 HLDA V; WS Code AS S143 HLDA VI; WS Code AS Ref.6 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | ITGAX |
| Purity | Protein A purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
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| Application Notes | This antibody is Cytof ready. |
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| Theoretical MW | 150 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Storage | Store at 4C. Do not freeze. |
| Buffer | PBS (pH 7.4) |
| Preservative | 0.09% Sodium Azide |
| Concentration | 1 mg/ml |
| Purity | Protein A purified |
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| Publication using NBP1-45018 | Applications | Species |
|---|---|---|
| Kim J, Jeong JH, Jung J et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis Rheumatology (Oxford) 4390-01-01 [PMID: 32163584] (IHC-P, Human) | IHC-P | Human |
Secondary Antibodies |
Isotype Controls |
Research Areas for CD11c Antibody (NBP1-45018)Find related products by research area.
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Read full blog post. |
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CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a... Read full blog post. |
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Adhesion Receptor Molecule CD11b/c is the Point of Entry for many Infectious Diseases Pathogenic microorganisms utilize a variety of cell surface receptors to gain entry into host cells and to bypass the natural defense mechanisms. One of the most prominent receptors used in this fashion is the leukocyte adhesion receptor CD11b/c. This... Read full blog post. |
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CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a... Read full blog post. |
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| Gene Symbol | ITGAX |
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP (monocyte gate).](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0001.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP (monocyte gate).")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) APC.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0002.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) APC.")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP-CyTM5.5.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0003.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP-CyTM5.5.")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PE.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0004.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PE.")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PE-CyTM7. .](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0005.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PE-CyTM7. .")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0007.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) PerCP.")
![Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) FITC.](http://images.novusbio.com/fullsize/CD11c-Antibody-BU15-Flow-Cytometry-NBP1-45018-img0008.jpg "Flow Cytometry: CD11c Antibody (BU15) [NBP1-45018] - Staining of human peripheral blood cells with anti-CD11c (BU15) FITC.")
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