CD117/c-kit Antibody (180627) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

SCF R is also known as the c-kit proto-oncogene protein and as CD117. Together with its ligand, stem cell factor (also called c-kit ligand or mast cell growth factor), SCF R plays an essential role in gametogenesis, melanogenesis, and hematopoiesis. SCF R is expressed in hematopoietic progenitor cells, normal B  and T lymphocyte progenitors, mast cells, germ cells, melanocytes, neurons, glial cells, placenta, kidney, lung, and gut. In addition, SCF R expression has also been reported in several human tumor cell lines (1,2).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Newt.

We have publications tested in 3 applications: ICC, IHC, IHC-P.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using MAB1356	Applications	Species
Hosaka K, Wang C, Zhang S et al. Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors Cancer communications (London, England) 2023-04-29 [PMID: 37120719]
T Tanaka, H Okuda, A Isonishi, Y Terada, M Kitabatake, T Shinjo, K Nishimura, S Takemura, H Furue, T Ito, K Tatsumi, A Wanaka Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway Nature Immunology, 2023-01-26;0(0):. 1/26/2023 [PMID: 36703006]
Mark L. Kovler, Andres J. Gonzalez Salazar, William B. Fulton, Peng Lu, Yukihiro Yamaguchi, Qinjie Zhou et al. Toll-like receptor 4–mediated enteric glia loss is critical for the development of necrotizing enterocolitis Science Translational Medicine 2021-09-22 [PMID: 34550727]
K Matsumoto, K Takata, D Yamada, H Usuda, K Wada, M Tada, Y Mishima, S Ishihara, S Horie, A Saitoh, S Kato Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice Scientific Reports, 2021-08-11;11(1):16276. 2021-08-11 [PMID: 34381165] (IHC, Mouse)	IHC	Mouse
JW Wu, X Zhang, R Sekiya, K Aoyagi, TS Li Immunohistochemical Analysis of Histone H3 Modification in Newt Tail Tissue Cells following Amputation Stem Cells International, 2021-01-05;2021(0):8828931. 2021-01-05 [PMID: 33505473] (IHC, Newt)	IHC	Newt
Ruihua Ma, Angelica S Martínez-Ramírez, Thomas L Borders, Fanding Gao, Beatriz Sosa-Pineda Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts eLife 2020-03-10 [PMID: 32154783]
T I, Y Sumita, T Yoshida, R Honma, M Iwatake, JLM Raudales, T Shizuno, S Kuroshima, H Masuda, M Seki, SD Tran, T Asahara, I Asahina Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands Stem Cell Res Ther, 2019-10-17;10(1):304. 2019-10-17 [PMID: 31623661] (IHC-P, Mouse)	IHC-P	Mouse
K Kishi, A Uchida, HM Takase, H Suzuki, M Kurohmaru, N Tsunekawa, M Kanai-Azum, SA Wood, Y Kanai Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice Reproduction, 2017-05-30;0(0):. 2017-05-30 [PMID: 28559472] (IHC, Mouse)	IHC	Mouse
Fang , Shentong, Wei , Jing, Pentinmikko , Nalle, Leinonen , Hannele, Salven , Petri Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell. PLoS Biol, 2012-10-16;10(10):e1001407. 2012-10-16 [PMID: 23091420] (IHC, Mouse)	IHC	Mouse
Yoshinori Sumita, Younan Liu, Saeed Khalili, Ola M. Maria, Dengsheng Xia, Sharon Key et al. Bone marrow-derived cells rescue salivary gland function in mice with head and neck irradiation The International Journal of Biochemistry & Cell Biology 2011-01-01 [PMID: 20933096]
Ling TY, Kuo MD, Li CL, Yu AL, Huang YH, Wu TJ, Lin YC, Chen SH, Yu J Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro. Proc. Natl. Acad. Sci. U.S.A., 2006-06-13;103(25):9530-5. 2006-06-13 [PMID: 16772384] (ICC, Mouse)	ICC	Mouse
Show All 11 Publications. Collapse Publications.

Array MAB1356

• CD117/c-kit Antibodies
• CD117/c-kit ELISA Kits
• CD117/c-kit Lysates
• CD117/c-kit Proteins
• CD117/c-kit Proteins and Enzymes
• CD117/c-kit ELISAs