CD117/c-kit Antibody (180627) [Phycoerythrin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

SCF R, also known as c-kit proto-oncogene protein and CD117, is a 145-160 kDa member of the type III tyrosine kinase family of proteins (1,2). It is expressed on hematopoietic and endothelial cell progenitors, mast cells, germ cells, melanocytes, trigeminal neurons, glial cells, placenta, kidney, lung, and gut. SCF R is a type I transmembrane glycoprotein that undergoes splicing during spermatogenesis. Two isoforms of 50 kDa and 30 kDa are generated that represent C-terminal intracellular functional products (3). SCF R also undergoes cleavage by select cell types, generating a 95-100 kDa soluble form (4). Over amino acids 25-519, mouse SCF R shares 73% and 87% amino acid sequence identity with human and rat SCF R, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 2 of 2.

Publications using FAB1356P	Applications	Species
Tamagawa-Mineoka R, Kishida T, Mazda O IL-21 Reduces Immediate Hypersensitivity Reactions in Mouse Skin by Suppressing Mast Cell Activation or IgE Production. J. Invest. Dermatol., 2011-03-24;131(7):1513-20. 2011-03-24 [PMID: 21430699] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Dai Y, Ashraf M, Zuo S, Uemura R, Dai YS, Wang Y, Haider HKh, Li T, Xu M Mobilized bone marrow progenitor cells serve as donors of cytoprotective genes for cardiac repair. J. Mol. Cell. Cardiol., 2007-12-07;44(3):607-17. 2007-12-07 [PMID: 18221754] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse

Array FAB1356P

• CD117/c-kit Antibodies
• CD117/c-kit ELISA Kits
• CD117/c-kit Lysates
• CD117/c-kit Proteins
• CD117/c-kit Proteins and Enzymes
• CD117/c-kit ELISAs