Name: CCL20/MIP-3 alpha Antibody (67310) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB360
Price: 459 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, B/N, ELISA(Cap)
Clone	67310
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB360U

Alexa Fluor 405 FAB360V

Alexa Fluor 488 FAB360G

Alexa Fluor 532 FAB360X

Alexa Fluor 594 FAB360T

Alexa Fluor 647 FAB360R

Alexa Fluor 700 FAB360N

Alexa Fluor 750 FAB360S

Allophycocyanin FAB360A

Biotin FAB360B

CoraFluor 1 FAB360CL1

DyLight 350 FAB360D

DyLight 405 FAB360E

DyLight 488 FAB360K

DyLight 550 FAB360L

DyLight 594 FAB360M

DyLight 650 FAB360W

DyLight 680 FAB360Y

DyLight 755 FAB360Z

HRP FAB360H

Janelia Fluor 525 FAB360JF525

Janelia Fluor 549 FAB360I

Janelia Fluor 635 FAB360JF635

Janelia Fluor 646 FAB360J

Janelia Fluor 669 FAB360JF669

PerCP FAB360C

mFluor Violet 450 SE FAB360MFV450

mFluor Violet 500 SE FAB360MFV500

mFluor Violet 610 SE FAB360MFV610

Catalog# & Formulation	Size	Price
Carrier Free MAB360-SP

Carrier Free MAB360-500

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB360U
Alexa Fluor 405	FAB360V
Alexa Fluor 488	FAB360G
Alexa Fluor 532	FAB360X
Alexa Fluor 594	FAB360T
Alexa Fluor 647	FAB360R
Alexa Fluor 700	FAB360N
Alexa Fluor 750	FAB360S
Allophycocyanin	FAB360A
Biotin	FAB360B
CoraFluor 1	FAB360CL1
DyLight 350	FAB360D
DyLight 405	FAB360E
DyLight 488	FAB360K
DyLight 550	FAB360L
DyLight 594	FAB360M
DyLight 650	FAB360W
DyLight 680	FAB360Y
DyLight 755	FAB360Z
HRP	FAB360H
Janelia Fluor 525	FAB360JF525
Janelia Fluor 549	FAB360I
Janelia Fluor 635	FAB360JF635
Janelia Fluor 646	FAB360J
Janelia Fluor 669	FAB360JF669
PerCP	FAB360C
mFluor Violet 450 SE	FAB360MFV450
mFluor Violet 500 SE	FAB360MFV500
mFluor Violet 610 SE	FAB360MFV610

CCL20/MIP-3 alpha Antibody (67310) [Unconjugated]

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CCL20/MIP-3 alpha Antibody (67310) [Unconjugated] Summary

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Publications for CCL20/MIP-3 alpha Antibody (MAB360)(45)

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Immunogen	E. coli-derived recombinant human CCL20/MIP-3 alpha Ala27-Met96 (Asn95Asp) Accession # P78556.1
Specificity	Detects human CCL20/MIP-3 alpha in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human (rh) CCL19, rhCXCL1, rhCCL16, rhCCL11, recombinant mouse CCL20/MIP-3 alpha , or recombinant rat CCL20/MIP-3 alpha is observed.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	CCL20
Purity Statement	Protein A or G purified from ascites
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB360	Applications	Species
Elabi, OF;Espa, E;Skovgård, K;Fanni, S;Cenci, MA; Ropinirole Cotreatment Prevents Perivascular Glial Recruitment in a Rat Model of L-DOPA-Induced Dyskinesia Cells 2023-07-14 [PMID: 37508522]
F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells bioRxiv : the preprint server for biology, 2023-02-13;0(0):. 2023-02-13 [PMID: 36789428] (Bioassay, Human)	Bioassay	Human
Hiroshi Kano, Kouji Izumi, Kaoru Hiratsuka, Ren Toriumi, Ryunosuke Nakagawa, Shuhei Aoyama et al. Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20–CCR6 axis Cancer Science 4/1/2023 [PMID: 36479732]
Benton KC, Wheeler DS, Kurtoglu B et al. Norepinephrine activates ?(1) -adrenergic receptors at the inner nuclear membrane in astrocytes Glia 2022-09-01 [PMID: 35589612]
C Morel, A Christophe, K Maguin-Gat, J Paoli, JD Turner, H Schroeder, N Grova Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: alpha-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders Toxics, 2022-04-06;10(4):. 4/6/2022 [PMID: 35448441]
P Esteves, B Allard, A Celle, I Dupin, E Maurat, O Ousova, M Thumerel, JW Dupuy, T Leste-Lass, R Marthan, PO Girodet, T Trian, P Berger Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium Cell Reports, 2022-03-29;38(13):110571. 2022-03-29 [PMID: 35354045] (Neutralization, Human)	Neutralization	Human
Xia L, Liu L, Cai Y et al. Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice Frontiers in Pharmacology 2022-01-28 [PMID: 35153737]
Liu X, Liu BL, Yang Q et al. Microglial ablation does not affect opioid-induced hyperalgesia in rodents Pain 2022-03-01 [PMID: 34433775]
Yang Liu, Huiqun Fu, Yan Wu, Binbin Nie, Fangyan Liu, Tianlong Wang et al. Elamipretide (SS-31) Improves Functional Connectivity in Hippocampus and Other Related Regions Following Prolonged Neuroinflammation Induced by Lipopolysaccharide in Aged Rats Frontiers in Aging Neuroscience 2021-03-01 [PMID: 33732135]
Choi YW, Kim YH, Oh SY et al. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer Advanced Science 1/4/2021 [PMID: 33643790]
Y Wang, Z Lyu, Y Qin, X Wang, L Sun, Y Zhang, L Gong, S Wu, S Han, Y Tang, Y Jia, DL Kwong, N Kam, XY Guan FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma Theranostics, 2020-09-16;10(25):11535-11548. 9/16/2020 [PMID: 33052231]
Anqi Li, Ningyue Zhang, Zhiming Zhao, Yali Chen, Liang Zhang Overexpression of B7‑H4 promotes renal cell carcinoma progression by recruiting tumor‑associated neutrophils via upregulation of CXCL8 Oncology Letters 2020-06-05 [PMID: 32724395]
Mike, J K, Pathipati, P Et al. Changes in arginase isoforms in a murine model of neonatal brain hypoxia-ischemia. Pediatr Res 3/1/2021 [PMID: 32464635]
M Nayrac, M Requena, C Loiseau, M Cazabat, B Suc, N Carrere, K Barange, L Alric, G Martin-Blo, J Izopet, P Delobel Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals Mucosal Immunol, 2020-04-28;0(0):. 2020-04-28 [PMID: 32346082] (Functional Assay, Human)	Functional Assay	Human
Anna Yu-Szu Huang, Junsung Woo, Debosmita Sardar, Brittney Lozzi, Navish A Bosquez Bosquez Huerta, Chia-Ching John Lin et al. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities Neuron 2020-06-01 [PMID: 32320644]
Bhavika B. Patel, Marilyn C. McNamara, Laura S. Pesquera-Colom, Emily M. Kozik, Jasmin Okuzonu, Nicole N. Hashemi et al. Recovery of Encapsulated Adult Neural Progenitor Cells from Microfluidic-Spun Hydrogel Fibers Enhances Proliferation and Neuronal Differentiation ACS Omega 2020-04-14 [PMID: 32309700]
Fadi Jacob, Ryan D. Salinas, Daniel Y. Zhang, Phuong T.T. Nguyen, Jordan G. Schnoll, Samuel Zheng Hao Wong et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity Cell 2020-01-01 [PMID: 31883794]
Sheu-Ran Choi, Ho-Jae Han, Alvin J. Beitz, Jang-Hern Lee Spinal Interleukin-1 beta Inhibits Astrocyte Cytochrome P450c17 Expression Which Controls the Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain Frontiers in Molecular Neuroscience 2019-06-20 [PMID: 31281242]
Alistair E. Govier-Cole, Rhiannon J. Wood, Jessica L. Fletcher, David G. Gonsalvez, Daniel Merlo, Holly S. Cate et al. Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation eNeuro 2019-04-26 [PMID: 31028086]
He Q, Gao Y, Wang, T et al. Deficiency of Yes-Associated Protein Induces Cataract in Mice Aging Dis. 4/1/2019 [PMID: 31011480]
Stefan Christopher Weise, Alejandro Villarreal, Stefanie Heidrich, Fariba Dehghanian, Christian Schachtrup, Sigrun Nestel et al. TGF beta -Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain Frontiers in Cellular Neuroscience 2018-11-28 [PMID: 30555301]
Goulao M, Ghosh B, Urban MW et al. Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury Glia 12/11/2018 [PMID: 30548313]
Seok Joon Won, Angela M. Minnella, Long Wu, Claire H. Eun, Eric Rome, Paco S. Herson et al. Cofilin-actin rod formation in neuronal processes after brain ischemia PLOS ONE 2018-10-16 [PMID: 30325927]
SU Vay, LJ Flitsch, M Rabenstein, R Rogall, S Blaschke, J Kleinhaus, N Reinert, A Bach, GR Fink, M Schroeter, MA Rueger The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo J Neuroinflammation, 2018-08-13;15(1):226. 8/13/2018 [PMID: 30103769]
EJ Sandquist, JJ Essner, DS Sakaguchi Xenotransplantation of adult hippocampal neural progenitors into the developing zebrafish for assessment of stem cell plasticity PLoS ONE, 2018-05-24;13(5):e0198025. 5/24/2018 [PMID: 29795671]
Swaathi Jayaraman, Michele Doucet, Scott L. Kominsky CITED2 attenuates macrophage recruitment concordant with the downregulation of CCL20 in breast cancer cells Oncology Letters 2017-11-15 [PMID: 29399152]
B Soto, T Gallastegi, C Rodríguez, J Martínez-G, JR Escudero, L Vila, M Camacho Circulating CCL20 as a New Biomarker of Abdominal Aortic Aneurysm Sci Rep, 2017-12-11;7(1):17331. 2017-12-11 [PMID: 29229985] (IHC-P, Human)	IHC-P	Human
C. Loiseau, M. Requena, M. Mavigner, M. Cazabat, N. Carrere, B. Suc et al. CCR6(-) regulatory T cells blunt the restoration of gut Th17 cells along the CCR6-CCL20 axis in treated HIV-1-infected individuals Mucosal Immunology 2016-09-01 [PMID: 26883727]
Sho Ikeda, Akihiro Kitadate, Mitsugu Ito, Fumito Abe, Miho Nara, Atsushi Watanabe et al. Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma Oncotarget 2016-03-22 [PMID: 26789110]
Robert Krencik, Kenton C. Hokanson, Aditi R. Narayan, Jill Dvornik, Gemma E. Rooney, Katherine A. Rauen et al. Dysregulation of astrocyte extracellular signaling in Costello syndrome Science Translational Medicine 2015-05-06 [PMID: 25947161]
Hagiwara , Kunie, Obayashi , Takeshi, Sakayori , Nobuyuki, Yamanishi , Emiko, Hayashi , Ryuhei, Osumi , Noriko, Nakazawa , Toru, Nishida , Kohji Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE, 2014-01-20;9(1):e84072. 1/20/2014 [PMID: 24465393]
Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, Liu Z Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy, 2013-12-04;10(2):257-68. 2013-12-04 [PMID: 24321786] (Neutralization, Human)	Neutralization	Human
Sarah C. Robins, Eric Trudel, Olivia Rotondi, Xiaohong Liu, Tina Djogo, Darya Kryzskaya et al. Evidence for NG2-glia Derived, Adult-Born Functional Neurons in the Hypothalamus PLoS ONE 2013-10-29 [PMID: 24205170]
Yung‐Wei Pan, Wenbin Wang, Zhengui Xia Assessment of Adult Neurogenesis in Mice Current Protocols in Toxicology 2013-06-07 [PMID: 23670864]
Céline Plachez, Kathleen Cato, Robert C McLeay, Yee Hsieh Evelyn Heng, Timothy L Bailey, Richard M Gronostajski et al. Expression of nuclear factor one A and -B in the olfactory bulb The Journal of Comparative Neurology 2012-10-01 [PMID: 22886731]
Miyagaki T, Sugaya M, Suga H, Kamata M, Ohmatsu H, Fujita H, Asano Y, Tada Y, Kadono T, Sato S IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma. Clin. Cancer Res., 2011-11-02;17(24):7529-38. 2011-11-02 [PMID: 22048239] (IHC-P, Human)	IHC-P	Human
Gruol DL, Puro A, Hao C et al. Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6. J Neuroimmunol. 9/2/2011 [PMID: 21890220]
Hu H, Kwun J, Aizenstein BD, Knechtle SJ Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 2009-06-27;87(12):1814-20. 2009-06-27 [PMID: 19543058] (Antibody Array Development, Human)	Antibody Array Development	Human
Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis. J. Immunol., 2008-11-15;181(10):7420-7. 2008-11-15 [PMID: 18981165] (IHC-Fr, Human)	IHC-Fr	Human
Baumforth KR, Birgersdotter A, Reynolds GM, Wei W, Kapatai G, Flavell JR, Kalk E, Piper K, Lee S, Machado L, Hadley K, Sundblad A, Sjoberg J, Bjorkholm M, Porwit AA, Yap LF, Teo S, Grundy RG, Young LS, Ernberg I, Woodman CB, Murray PG Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. Am. J. Pathol., 2008-05-23;173(1):195-204. 2008-05-23 [PMID: 18502823] (Bioassay, Human)	Bioassay	Human
Huang SJ, Chen CP, Schatz F, Rahman M, Abrahams VM, Lockwood CJ Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua. J. Pathol., 2008-02-01;214(3):328-36. 2008-02-01 [PMID: 18069648] (ELISA Development, IHC-Fr, Human)	ELISA Development, IHC-Fr	Human
Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Clin. Exp. Immunol., 2007-10-09;150(3):567-75. 2007-10-09 [PMID: 17924972] (ELISA Development, Human)	ELISA Development	Human
Lecureuil C, Combadiere B, Mazoyer E, Bonduelle O, Samri A, Autran B, Debre P, Combadiere C Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients. Blood, 2006-12-29;109(9):3649-57. 2006-12-29 [PMID: 17197436] (ELISA Development, Human)	ELISA Development	Human
Bosco MC, Puppo M, Santangelo C, Anfosso L, Pfeffer U, Fardin P, Battaglia F, Varesio L Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene. J. Immunol., 2006-08-01;177(3):1941-55. 2006-08-01 [PMID: 16849508] (ICC, Human)	ICC	Human
Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G Th2 cytokine response in Major Depressive Disorder patients before treatment. J. Neuroimmunol., 2006-02-02;172(1):156-65. 2006-02-02 [PMID: 16457895] (ELISA Development, Human)	ELISA Development	Human
Show All 45 Publications. Collapse Publications.

Gene Symbol	CCL20
Uniprot	P78556.1()