Caveolin-3 Antibody

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publications 1 - 2 of 2.

Publications using NB110-5029	Applications	Species
Yis U, Diniz G, Hazan F et al. Childhood onset limb-girdle muscular dystrophies in the Aegean part of Turkey Acta Myol. 2018-08-31 [PMID: 30838351] (IHC-P, Human)	IHC-P	Human
Diniz G, Eryasar G, Ture S et al. A regional panorama of dysferlinopathies. Turk Patoloji Derg 2012-01-01 [PMID: 23011829]

Array NB110-5029

• Caveolin-3 Antibodies
• Caveolin-3 Lysates
• Caveolin-3 Proteins