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carabin Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: carabin Antibody [NBP2-49616] - Immunofluorescent staining of human cell line Hep G2 shows localization to nuclear bodies.
Orthogonal Strategies: Immunohistochemistry-Paraffin: carabin Antibody [NBP2-49616] - Staining in human tonsil and cerebral cortex tissues using anti-TBC1D10C antibody. Corresponding TBC1D10C RNA-seq data are ...read more
Immunohistochemistry-Paraffin: carabin Antibody [NBP2-49616] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: carabin Antibody [NBP2-49616] - Staining of human tonsil shows high expression.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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carabin Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: DLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEPGPGHPPADLIRQREMKWVEM
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TBC1D10C
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
carabin Recombinant Protein Antigen (NBP2-49616PEP)

Reactivity Notes

Rat (84%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for carabin Antibody

  • carabin
  • FLJ00332
  • MGC46488
  • TBC1 domain family member 10C
  • TBC1 domain family, member 10C

Background

Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TBC1D10C