Canine IL-12/IL-23 p40 DuoSet ELISA, 15 Plate Summary
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
Intra-Assay
Spike Recovery
Sample Volume
Gene
IL12B
Applications/Dilutions
Dilutions
Application Notes
No significant interference observed with available related molecules.
Publications
Packaging, Storage & Formulations
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Canine IL-12/IL-23 p40 DuoSet ELISA, 15 Plate
Background
Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.
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Publications for IL-12/IL-23 p40 (DY1969)(6)
We have publications tested in 1 confirmed species: Canine.
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Showing Publications 1 -
6 of 6.
Publications using DY1969
Applications
Species
GT Rebech, JP Bragato, SF Costa, JH de Freitas, MO Dos Santos, MF Soares, FR Eugênio, PSP Dos Santos, VMF de Lima miR-148a regulation interferes in inflammatory cytokine and parasitic load in canine leishmaniasis PloS Neglected Tropical Diseases, 2023-01-31;17(1):e0011039. 2023-01-31 [PMID: 36719867] (Canine)
Canine
S Kim, YS Hyun, HT Park, MK Shin, HS Yoo Mycobacterium intracellulare induces a Th17 immune response via M1-like macrophage polarization in canine peripheral blood mononuclear cells Scientific Reports, 2022-07-12;12(1):11818. 2022-07-12 [PMID: 35821058] (Canine)
Canine
LM Melo, JP Bragato, GL Venturin, GT Rebech, SF Costa, LE Garcia, FL Lopes, FR Eugênio, PS Patto Dos, VMF de Lima Induction of miR 21 impairs the anti-Leishmania response through inhibition of IL-12 in canine splenic leukocytes PLoS ONE, 2019-12-11;14(12):e0226192. 2019-12-11 [PMID: 31825987] (Canine)
Canine
U Lampreht T, S Kos, U Kamensek, M Ota, N Tozon, G Sersa, M Cemazar Antitumor effect of antibiotic resistance gene-free plasmids encoding interleukin-12 in canine melanoma model Cancer Gene Ther., 2018-03-29;0(0):. 2018-03-29 [PMID: 29593358] (Canine)
Canine
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge PLoS ONE, 2016-08-24;11(8):e0161169. 2016-08-24 [PMID: 27556586] (Canine)
Canine
Mito K, Sugiura K, Ueda K, Hori T, Akazawa T, Yamate J, Nakagawa H, Hatoya S, Inaba M, Inoue N, Ikehara S, Inaba T IFN-gamma markedly cooperates with intratumoral dendritic cell vaccine in dog tumor models.. Cancer Res., 2010-09-07;70(18):7093-101. 2010-09-07 [PMID: 20823157] (Canine)
Canine
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