Canine IL-10 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

We have publications tested in 1 confirmed species: Canine.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using CA1000	Applications	Species
S Kim, YS Hyun, HT Park, MK Shin, HS Yoo Mycobacterium intracellulare induces a Th17 immune response via M1-like macrophage polarization in canine peripheral blood mononuclear cells Scientific Reports, 2022-07-12;12(1):11818. 2022-07-12 [PMID: 35821058] (Canine)		Canine
E Gugliandol, P Licata, AF Peritore, R Siracusa, R D'Amico, M Cordaro, R Fusco, D Impellizze, R Di Paola, S Cuzzocrea, R Crupi, CD Interlandi Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood Veterinary sciences, 2021-09-04;8(9):. 2021-09-04 [PMID: 34564578] (Canine)		Canine
H Suzuki, N Oshima, T Watari Effect of modified ultrafiltration on cytokines and hemoconcentration in dogs undergoing cardiopulmonary bypass J Vet Med Sci, 2020-10-05;0(0):. 2020-10-05 [PMID: 33012753] (Canine)		Canine
A Kathrani, E Hall A preliminary study assessing cytokine production following ex vivo stimulation of whole blood with diet in dogs with chronic enteropathy BMC Vet. Res., 2019-06-04;15(1):185. 2019-06-04 [PMID: 31164117] (Canine)		Canine
SH Lee, JC Ra, HJ Oh, MJ Kim, EMN Setyawan, YB Choi, JW Yang, SK Kang, SH Han, GA Kim, BC Lee Clinical Assessment of Intravenous Endothelial Progenitor Cell Transplantation in Dogs Cell Transplant, 2019-04-24;0(0):9636897188216. 2019-04-24 [PMID: 31018670] (Canine)		Canine
J Junginger, K Raue, K Wolf, E Janecek, VM Stein, A Tipold, AR Günzel-Ape, C Strube, M Hewicker-T Zoonotic intestinal helminths interact with the canine immune system by modulating T cell responses and preventing dendritic cell maturation Sci Rep, 2017-09-04;7(1):10310. 2017-09-04 [PMID: 28871165] (Canine)		Canine
L Leclerc, C Thorin, J Flanagan, V Biourge, S Serisier, P Nguyen Higher neonatal growth rate and body condition score at 7�months are predictive factors of obesity in adult female Beagle dogs BMC Vet. Res., 2017-04-13;13(1):104. 2017-04-13 [PMID: 28407742] (Canine)		Canine
C R Bjørnvad Immunometabolic parameters in overweight dogs during weight loss with or without an exercise program Domest. Anim. Endocrinol., 2016-11-11;59(0):58-66. 2016-11-11 [PMID: 27951413] (Canine)		Canine
Ferreira J, Silva L, Longo-Maugeri I, Katz S, Barbieri C Use of a recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi for the Immunotherapy of canine visceral Leishmaniasis. PLoS Negl Trop Dis, 2014-03-13;8(3):e2729. 2014-03-13 [PMID: 24625516] (Canine)		Canine
Esch K, Juelsgaard R, Martinez P, Jones D, Petersen C Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function. J Immunol, 2013-10-23;191(11):5542-50. 2013-10-23 [PMID: 24154626] (Canine)		Canine
Travi BL, Osorio EY, Saldarriaga OA Clinical, parasitologic, and immunologic evolution in dogs experimentally infected with sand fly-derived Leishmania chagasi promastigotes. Am. J. Trop. Med. Hyg., 2009-12-01;81(6):994-1003. 2009-12-01 [PMID: 19996427] (Canine)		Canine
Lin TY, London CA A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet. Immunol. Immunopathol., 2006-10-06;114(3):320-34. 2006-10-06 [PMID: 17027994] (Canine)		Canine
Kjelgaard-Hansen M, Luntang-Jensen M, Willesen J, Jensen AL Measurement of serum interleukin-10 in the dog. Vet. J., 2006-02-03;173(2):361-5. 2006-02-03 [PMID: 16459112] (Canine)		Canine
Show All 13 Publications. Collapse Publications.

Array CA1000

• IL-10 Antibodies
• IL-10 Antibody Pair
• IL-10 ELISA Kits
• IL-10 Lysate
• IL-10 Proteins
• IL-10 Proteins and Enzymes
• IL-10 ELISAs