Canine IL-10 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

We have publications tested in 1 confirmed species: Canine.

Showing Publications 1 - 10 of 15. Show All 15 Publications. Collapse Publications.

Publications using DY735	Applications	Species
Costa, SF;Soares, MF;Poleto Bragato, J;Dos Santos, MO;Rebech, GT;de Freitas, JH;de Lima, VMF; MicroRNA-194 regulates parasitic load and IL-1?-dependent nitric oxide production in the peripheral blood mononuclear cells of dogs with leishmaniasis PLoS neglected tropical diseases 2024-01-01 [PMID: 38241360] (Canine)		Canine
M Pelst, C Höbart, H de Rooster, B Devriendt, E Cox Immortalised canine buccal epithelial cells' CXCL8 secretion is affected by allergen extracts, Toll-like receptor ligands, IL-17A and calcitriol Veterinary research, 2022-09-13;53(1):72. 2022-09-13 [PMID: 36100942] (Canine)		Canine
JP Bragato, GT Rebech, JH Freitas, MOD Santos, SF Costa, FR Eugênio, PSPD Santos, VMF de Lima miRNA-21 regulates CD69 and IL-10 expression in canine leishmaniasis PLoS ONE, 2022-03-24;17(3):e0265192. 2022-03-24 [PMID: 35324917] (Canine)		Canine
JK Abbott, SK Chan, M MacBeth, JL Crooks, C Hancock, V Knight, EW Gelfand Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles PLoS ONE, 2022-03-22;17(3):e0265852. 2022-03-22 [PMID: 35316278] (Canine)		Canine
MT Verde, S Villanueva, A Loste, D Marteles, D Pereboom, T Conde, A Fernández Comparison of circulating CD4+, CD8+ lymphocytes and cytokine profiles between dogs with atopic dermatitis and healthy dogs Research in Veterinary Science, 2022-01-29;145(0):13-20. 2022-01-29 [PMID: 35134678] (Canine)		Canine
PJ Alcolea, A Alonso, A Esteban, P Peris, A Cortés, JA Castillo, V Larraga IL12 p35 and p40 subunit genes administered as pPAL plasmid constructs do not improve protection of pPAL-LACK vaccine against canine leishmaniasis PLoS ONE, 2019-02-22;14(2):e0212136. 2019-02-22 [PMID: 30794597] (Canine)		Canine
KL Oliveira S, V Marin Chik, G Luvizotto, AA Correa Lea, BF de Almeida, F De Rezende, PSP Dos Santos, G Fabrino Ma, VMF De Lima PD-1 and PD-L1 regulate cellular immunity in canine visceral leishmaniasis Comp. Immunol. Microbiol. Infect. Dis., 2018-12-14;62(0):76-87. 2018-12-14 [PMID: 30711051] (Canine)		Canine
Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Via Multiple Distinct Biochemical Pathways Stem Cells Dev., 2016-12-22;0(0):. 2016-12-22 [PMID: 27842458] (Canine)		Canine
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge PLoS ONE, 2016-08-24;11(8):e0161169. 2016-08-24 [PMID: 27556586] (Canine)		Canine
JA MacDiarmid, V Langova, D Bailey, ST Pattison, SL Pattison, N Christense, LR Armstrong, VN Brahmbhatt, K Smolarczyk, MT Harrison, M Costa, NB Mugridge, I Sedliarou, NA Grimes, DL Kiss, B Stillman, CL Hann, GL Gallia, RM Graham, H Brahmbhatt Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model PLoS ONE, 2016-04-06;11(4):e0151832. 2016-04-06 [PMID: 27050167] (Canine)		Canine
Shahbazi M, Zahedifard F, Taheri T, Taslimi Y, Jamshidi S, Shirian S, Mahdavi N, Hassankhani M, Daneshbod Y, Zarkesh-Esfahani S, Papadopoulou B, Rafati S Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis. PLoS ONE, 2015-07-21;10(7):e0132794. 2015-07-21 [PMID: 26197085] (Canine)		Canine
Costa-Pereira C, Moreira M, Soares R, Marteleto B, Ribeiro V, Franca-Dias M, Cardoso L, Viana K, Giunchetti R, Martins-Filho O, Araujo M One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis. BMC Vet Res, 2015-04-11;11(0):92. 2015-04-11 [PMID: 25880646] (Canine)		Canine
Figueiredo M, Deoti B, Amorim I, Pinto A, Moraes A, Carvalho C, da Silva S, de Assis A, de Faria A, Tafuri W Expression of regulatory T cells in jejunum, colon, and cervical and mesenteric lymph nodes of dogs naturally infected with Leishmania infantum. Infect Immun, 2014-06-16;82(9):3704-12. 2014-06-16 [PMID: 24935975] (Canine)		Canine
Aparicio-Burgos JE, Ochoa-Garcia L, Zepeda-Escobar JA, Gupta S, Dhiman M, Martinez JS, de Oca-Jimenez RM, Val Arreola M, Barbabosa-Pliego A, Vazquez-Chagoyan JC, Garg NJ Testing the efficacy of a multi-component DNA-prime/DNA-boost vaccine against Trypanosoma cruzi infection in dogs. PLoS Negl Trop Dis, 2011-05-17;5(5):e1050. 2011-05-17 [PMID: 21625470] (Canine)		Canine
Fernandes AP, Costa MM, Coelho EA, Michalick MS, de Freitas E, Melo MN, Luiz Tafuri W, Resende Dde M, Hermont V, Abrantes Cde F, Gazzinelli RT Protective immunity against challenge with Leishmania (Leishmania) chagasi in beagle dogs vaccinated with recombinant A2 protein. Vaccine, 2008-09-09;26(46):5888-95. 2008-09-09 [PMID: 18786587] (Canine)		Canine
Show All 15 Publications. Collapse Publications.

Array DY735

• IL-10 Antibodies
• IL-10 Antibody Pair
• IL-10 ELISA Kits
• IL-10 Lysate
• IL-10 Proteins
• IL-10 Proteins and Enzymes
• IL-10 ELISAs