BMP-7 Antibody (164313) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

BMP-7, or osteogenic protein 1 (OP-1), is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily. BMPs regulate cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs, and growth, differentiation, chemotaxis and apoptosis of various cell types. Biologically active BMP-7 is a disulfide-linked homodimer. Cellular responses to BMP-7 have been shown to be mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA Detection, Western Blot.

Showing Publications 1 - 8 of 8.

Publications using MAB3542	Applications	Species
RL Cate, N di Clement, C Racine, NP Groome, RB Pepinsky, A Whitty The anti-M�llerian hormone prodomain is displaced from the hormone/prodomain complex upon bivalent binding to the hormone receptor The Journal of Biological Chemistry, 2021-11-19;0(0):101429. 2021-11-19 [PMID: 34801555] (ELISA Detection, Human)	ELISA Detection	Human
Seonghun Kim, Cheol-Hee Jeong, Sang Hyun Song, Jo Eun Um, Hyun Sil Kim, Jun Seop Yun et al. Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition Frontiers in Pharmacology 11/19/2020 [PMID: 33364962]
Aurore Bouty, Kelly Walton, Nurin Aisyiyah Listyasari, Gorjana Robevska, Jocelyn Van den Bergen, Ardy Santosa et al. Functional Characterization of Two New Variants in the Bone Morphogenetic Protein 7 Prodomain in Two Pairs of Monozygotic Twins With Hypospadias Journal of the Endocrine Society 4/1/2019 [PMID: 30963139]
Wohl A, Troilo H, Collins R, Baldock C, Sengle G Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1. J Biol Chem, 2016-04-08;291(24):12732-46. 4/8/2016 [PMID: 27059954]
Valérie Camara-Clayette, Serge Koscielny, Sébastien Roux, Thierry Lamy, Jacques Bosq, Marc Bernard et al. BMP7 Expression Correlates with Secondary Drug Resistance in Mantle Cell Lymphoma PLoS ONE 9/12/2013 [PMID: 24069261]
Imran Khan, Neeraj Kumar, Ila Pant, Sivakrishna Narra, Paturu Kondaiah Activation of TGF-beta Pathway by Areca Nut Constituents: A Possible Cause of Oral Submucous Fibrosis PLoS ONE 12/19/2012 [PMID: 23284772]
Péter Csomor, Balázs Liktor, Bálint Liktor, Zoltán Szekanecz, István Sziklai, Tamás Karosi Expression of bone morphogenetic protein 2, 4, 5, and 7 correlates with histological activity of otosclerotic foci Acta Oto-Laryngologica 6/1/2012 [PMID: 22385409]
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res., 2005-09-15;65(18):8274-85. 2005-09-15 [PMID: 16166304] (Western Blot, Human)	Western Blot	Human

Array MAB3542

• BMP-7 Antibodies
• BMP-7 ELISA Kits
• BMP-7 Lysate
• BMP-7 Proteins
• BMP-7 ELISAs
• BMP-7 Proteins and Enzymes