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Bcl-2 related protein A1 Antibody (OTI3D10) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
OTI3D10
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70246AF350
Alexa Fluor 405
NBP2-70246AF405
Alexa Fluor 488
NBP2-70246AF488
Alexa Fluor 532
NBP2-70246AF532
Alexa Fluor 594
NBP2-70246AF594
Alexa Fluor 647
NBP2-70246AF647
Alexa Fluor 700
NBP2-70246AF700
Alexa Fluor 750
NBP2-70246AF750
Biotin
NBP2-70246B
CoraFluor 1
NBP2-70246CL1
DyLight 350
NBP2-70246UV
DyLight 405
NBP2-70246V
DyLight 488
NBP2-70246G
DyLight 550
NBP2-70246R
DyLight 594
NBP2-70246DL594
DyLight 650
NBP2-70246C
DyLight 755
NBP2-70246IR
HRP
NBP2-70246H
Janelia Fluor 525
NBP2-70246JF525
Janelia Fluor 585
NBP2-70246JF585
Janelia Fluor 635
NBP2-70246JF635
Janelia Fluor 669
NBP2-70246JF669
Unconjugated
NBP2-46568
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46568
Azide and BSA Free
NBP2-70246
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Bcl-2 related protein A1 Antibody (OTI3D10) [DyLight 680] Summary

Immunogen
Full length recombinant protein of human Bcl-2 related protein A1 (NP_004040) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BCL2A1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Bcl-2 related protein A1 Antibody (OTI3D10) [DyLight 680]

  • ACC-1
  • ACC-2
  • Bcl-2 related protein A1
  • BCL2A1
  • Bcl2L5
  • Bcl2-L-5
  • BCL2L5HBPA1
  • Bcl-2-like protein 5
  • BCL2-related protein A1
  • Bfl-1
  • BFL1bcl-2-related protein A1
  • GRS
  • GRSbcl2-L-5
  • hematopoietic BCL2-related protein A1
  • Hemopoietic-specific early response protein
  • Protein BFL-1
  • Protein GRS

Background

Bcl-2 related protein A1; also known as Bcl2A1 and Bfl1, is an anti-apoptotic Bcl-2 family member preferentially expressed in hematopoietic and endothelial cells (1). Bfl1 is involved in a variety of cellular activities such as embryonic development, homeostatis and tumorigenesis. Expression of Bfl1 is stimulated by NF-kB in response to inflammatory stimuli and is up-regulated by TNF-alpha, IL1-beta, IGF1, GMC-SF, CD40 and phorbol ester (2-3). Blf1 has also been shown to reduce the release of pro-apoptotic cytochrome c from the mitochondria, block caspase activation and suppress apoptosis induced by p53 (4-5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BCL2A1