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Azurocidin/CAP37/HBP Antibody

Images

 
Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP3-16991] - Analysis in human bone marrow and pancreas tissues using Anti-AZU1 antibody. Corresponding AZU1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP3-16991] - Staining of human bone marrow shows high expression.
Immunohistochemistry-Paraffin: Azurocidin/CAP37/HBP Antibody [NBP3-16991] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Azurocidin/CAP37/HBP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: ALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AZU1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Azurocidin/CAP37/HBP Antibody

  • AZAMP
  • AZU
  • AZU1
  • azurocidin 1
  • Azurocidin
  • CAP37
  • CAP37Heparin-binding protein
  • cationic antimicrobial protein 37
  • HBP
  • HBPCationic antimicrobial protein CAP37
  • HUMAZUR
  • NAZC
  • neutrophil azurocidin

Background

Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AZU1