ATP6AP1 Antibody (3A2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00000537-M01	Applications	Species
Sekimizu M, Yoshida A, Mitani S et al. Frequent mutations of genes encoding vacuolar H+ -ATPase components in granular cell tumors. Genes Chromosomes Cancer. 2019-01-09 [PMID: 30597645]
Saw NM, Kang SY, Parsaud L et al. Vacuolar H+-ATPase subunit Voa1 and Voa2 cooperatively regulate secretory vesicle acidification, transmitter uptake and storage. Mol Biol Cell. 2011-07-27 [PMID: 21795392]

Array H00000537-M01

• ATP6AP1 Antibodies
• ATP6AP1 Lysate
• ATP6AP1 Protein