Angiopoietin-like Protein 4/ANGPTL4 Antibody [Biotin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ANGPTL4, also known as PPAR gamma angiopoietin-related protein (PGAR), hepatic fibrinogen/angiopoietin-related protein (HFARP) and fasting-induced adipose factor (FIAF), is a secreted protein that shares structural homology with angiopoietins. It contains an N-terminal coiled-coil region that mediates covalent homo-oligomerization and a C-terminal fibrinogen-like domain. ANGPTL4 undergoes proteolytic processing and releases the C-terminal domain, which circulates as a monomer. At least 2 additional splice isoforms exist. ANGPTL4 is most highly expressed in adipose tissues. Its expression is up-regulated in endothelial cells and cardiomyocytes during hypoxia. ANGPTL4 is involved in the regulation of lipid and glucose metabolism. It has also been associated with angiogenesis. The amino acid sequence of human ANGPTL4 is 81%, 76% and 81% identical to that of porcine, mouse and canine ANGPTL4, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA Detection, ELISA Development, ELISA Development (Detection).

Showing Publications 1 - 7 of 7.

Publications using BAF3485	Applications	Species
BW van der Ko, RG Vink, JWE Jocken, NJT Roumans, GH Goossens, ECM Mariman, MA van Baak, EE Blaak Effect of diet-induced weight loss on angiopoietin-like protein 4 and adipose tissue lipid metabolism in overweight and obese humans Physiol Rep, 2018-07-01;6(13):e13735. 2018-07-01 [PMID: 29998530] (ELISA Development (Detection), Human)	ELISA Development (Detection)	Human
EG Gruppen, S Kersten, RPF Dullaart Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation Lipids Health Dis, 2018-03-27;17(1):60. 2018-03-27 [PMID: 29587751] (ELISA Development (Detection), Human)	ELISA Development (Detection)	Human
W Dijk, S Schutte, EO Aarts, IMC Janssen, L Afman, S Kersten Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue J Clin Lipidol, 2018-02-17;0(0):. 2018-02-17 [PMID: 29555209] (ELISA Detection, Human)	ELISA Detection	Human
Wieneke Dijk, Markus Heine, Laurent Vergnes, Mariëtte R Boon, Gert Schaart, Matthijs K C Hesselink et al. ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure eLife 2015-10-17 [PMID: 26476336]
Nathanja Tjeerdema, Anastasia Georgiadi, Jacqueline T Jonker, Marjolijn van Glabbeek, Reza Alizadeh Alizadeh Dehnavi, Jouke T Tamsma et al. Inflammation increases plasma angiopoietin-like protein 4 in patients with the metabolic syndrome and type 2 diabetes BMJ Open Diabetes Research & Care 2014-12-03 [PMID: 25512873]
Alex S, Lange K, Amolo T, Grinstead J, Haakonsson A, Szalowska E, Koppen A, Mudde K, Haenen D, Al-Lahham S, Roelofsen H, Houtman R, van der Burg B, Mandrup S, Bonvin A, Kalkhoven E, Muller M, Hooiveld G, Kersten S Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor gamma. Mol Cell Biol, 2013-01-22;33(7):1303-16. 2013-01-22 [PMID: 23339868] (ELISA Development (Detection), Human)	ELISA Development (Detection)	Human
Kersten S, Lichtenstein L, Steenbergen E, Mudde K, Hendriks HF, Hesselink MK, Schrauwen P, Muller M Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids. Arterioscler. Thromb. Vasc. Biol., 2009-04-02;29(6):969-74. 2009-04-02 [PMID: 19342599] (ELISA Development, Human)	ELISA Development	Human

Array BAF3485

• Angiopoietin-like Protein 4/ANGPTL4 Antibodies
• Angiopoietin-like Protein 4/ANGPTL4 ELISA Kits
• Angiopoietin-like Protein 4/ANGPTL4 Lysate
• Angiopoietin-like Protein 4/ANGPTL4 Proteins and Enzymes
• Angiopoietin-like Protein 4/ANGPTL4 ELISAs