alpha-Fetoprotein/AFP Antibody (189506) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

AFP ( alpha -Fetoprotein) is a 69-73 kDa member of the ALB/AFP/VDB family of proteins. alpha -Fetoprotein is a major plasma protein in the fetus. Its concentration is normally low in the adult except when produced by certain tumors. It is secreted by fetal liver and serves as a carrier molecule for phytoestrogens, heavy metals (Cu and Ni), estrogen and fatty acids. Mature human AFP is 591 amino acids (aa) in length. It contains three albumin domains (aa 19-210, 211-402 and 403-601), plus 15 intrachain disulfide bonds. Mature human AFP shares approximately 66% aa identity with mouse AFP.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Pan troglodytes (Chimpanzee).

We have publications tested in 6 applications: Differentiation, Flow Cytometry, ICC, IHC, Immunocytochemistry, Western Blot.

Showing Publications 1 - 10 of 21. Show All 21 Publications. Collapse Publications.

Publications using MAB1369	Applications	Species
Karvas, RM;Zemke, JE;Ali, SS;Upton, E;Sane, E;Fischer, LA;Dong, C;Park, KM;Wang, F;Park, K;Hao, S;Chew, B;Meyer, B;Zhou, C;Dietmann, S;Theunissen, TW; 3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages Cell stem cell 2023-09-07 [PMID: 37683602] (Immunocytochemistry, Human)	Immunocytochemistry	Human
J Lotila, T Hyvärinen, H Skottman, L Airas, S Narkilahti, S Hagman Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient Oncogene, 2022-07-11;63(0):102865. 2022-07-11 [PMID: 35843021] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
C Banal, N Lefort Generation and characterization of IMAGINi013-A, an induced pluripotent stem cell line generated from a healthy donor Stem Cell Research, 2022-03-21;61(0):102755. 2022-03-21 [PMID: 35334405] (ICC, Human)	ICC	Human
NY Choi, Y Lee, YS Park, K Ko, B Park, YG Koh Establishment of an integration-free human induced pluripotent stem cell line (TJCi001-A) from normal bone marrow-derived mesenchymal stem cells Stem Cell Research, 2021-08-03;55(0):102484. 2021-08-03 [PMID: 34371346] (ICC, Human)	ICC	Human
Christian A Di Buduo, Pierre-Alexandre Laurent, Carlo Zaninetti, Larissa Lordier, Paolo M Soprano, Aikaterini Ntai et al. Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients eLife 6/1/2021 [PMID: 34059198]
C Banal, E Quelennec, W Bertani-To, N Gacem, J Amiel, S Marlin, F Petit, V Pingault, N Lefort, N Bondurand Generation of an iPSC line (IMAGINi022-A) from a patient carrying a SOX10 missense mutation and presenting with deafness, depigmentation and progressive neurological impairment Stem Cell Res, 2020-08-02;48(0):101936. 2020-08-02 [PMID: 32795927] (ICC, Human)	ICC	Human
G Menara, N Lefort, C Antignac, G Mollet Generation of an induced pluripotent stem cell (iPSC) line (IMAGINi007) from a patient with steroid-resistant nephrotic syndrome carrying the homozygous p.R138Q mutation in the podocin-encoding NPHS2 gene Stem Cell Res, 2020-06-18;46(0):101878. 2020-06-18 [PMID: 32585588] (ICC, Human)	ICC	Human
R Kitajima, R Nakai, T Imamura, T Kameda, D Kozuka, H Hirai, H Ito, H Imai, M Imamura Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells Stem Cell Res, 2020-02-28;44(0):101749. 2020-02-28 [PMID: 32151953] (ICC, Pan troglodytes (Chimpanzee))	ICC	Pan troglodytes (Chimpanzee)
Mehdi Shafa, Tylor Walsh, Krishna Morgan Panchalingam, Thomas Richardson, Laura Menendez, Xinghui Tian et al. Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells International Journal of Molecular Sciences 12/23/2019 [PMID: 31877913]
S Kaur, AG Abu-Shahba, RO Paananen, H Hongisto, H Hiidenmaa, H Skottman, R Seppänen-K, B Mannerströ Small non-coding RNA landscape of extracellular vesicles from human stem cells Sci Rep, 2018-10-19;8(1):15503. 2018-10-19 [PMID: 30341351] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
J Barnes, F Salas, R Mokhtari, H Dolstra, E Pedrosa, HM Lachman Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells Mol Autism, 2018-08-15;9(0):44. 2018-08-15 [PMID: 30147856] (IHC, Human)	IHC	Human
R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata) Sci Rep, 2018-08-15;8(1):12187. 8/15/2018 [PMID: 30111816]
M Shafa, F Yang, T Fellner, MS Rao, BA Baghbadera Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers Front Med (Lausanne), 2018-03-15;5(0):69. 2018-03-15 [PMID: 29600249] (ICC, Human)	ICC	Human
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells Nat Commun, 2016-12-09;7(0):13602. 2016-12-09 [PMID: 27934856] (Western Blot, Human)	Western Blot	Human
A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells PLoS ONE, 2016-09-08;11(9):e0161229. 2016-09-08 [PMID: 27606941] (IHC, Human)	IHC	Human
Behnam Ahmadian Baghbaderani, Adhikarla Syama, Renuka Sivapatham, Ying Pei, Odity Mukherjee, Thomas Fellner et al. Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications Stem Cell Reviews and Reports 8/1/2016 [PMID: 27283945]
Wren M, Zhao J, Liu C, Murray M, Atagi Y, Davis M, Fu Y, Okano H, Ogaki K, Strongosky A, Tacik P, Rademakers R, Ross O, Dickson D, Wszolek Z, Kanekiyo T, Bu G Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells. Mol Neurodegener, 2015-09-15;10(0):46. 2015-09-15 [PMID: 26373282] (IHC, Human)	IHC	Human
Onuma , Yasuko, Higuchi , Kumiko, Aiki , Yasuhiko, Shu , Yujing, Asada , Masahiro, Asashima , Makoto, Suzuki , Masashi, Imamura , Toru, Ito , Yuzuru A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture. PLoS ONE, 2015-04-07;10(4):e0118931. 2015-04-07 [PMID: 25850016] (ICC, Human)	ICC	Human
Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE, Dolznig H, Madel U, Feichtinger W, Atala A, Hengstschlager M Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Oncogene, 2009-11-23;29(7):966-77. 2009-11-23 [PMID: 19935716] (ICC, Human)	ICC	Human
Vallier L, Reynolds D, Pedersen RA Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev. Biol., 2004-11-15;275(2):403-21. 2004-11-15 [PMID: 15501227] (ICC, Human)	ICC	Human
Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum., 2004-08-01;50(8):2633-9. 2004-08-01 [PMID: 15334478] (ICC, Human)	ICC	Human
Show All 21 Publications. Collapse Publications.

Array MAB1369

• alpha-Fetoprotein/AFP Antibodies
• alpha-Fetoprotein/AFP Antibody Pair
• alpha-Fetoprotein/AFP ELISA Kits
• alpha-Fetoprotein/AFP Lysate
• alpha-Fetoprotein/AFP Proteins
• alpha-Fetoprotein/AFP ELISAs