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Aldolase C Antibody

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Western Blot: Aldolase C Antibody [NBP2-15346] - Various tissue extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Aldolase C antibody [N1C1] diluted at 1:1000. The HRP-conjugated ...read more
Immunohistochemistry-Frozen: Aldolase C Antibody [NBP2-15346] - Frozen-sectioned adult mouse cerebellum. Green: Aldolase C protein stained by Aldolase C antibody [N1C1] diluted at 1:250. Red: NeuN, stained by NeuN ...read more
Western Blot: Aldolase C Antibody [NBP2-15346] - Sample (30 ug of whole cell lysate) A: U87-MG B: MCF-7 10% SDS PAGE; antibody diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Ch, PmSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Aldolase C Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Aldolase C. The exact sequence is proprietary.
Marker
pan-Astrocyte Marker
Predicted Species
Porcine (100%), Bovine (100%), Chicken (92%), Canine (100%), Primate (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ALDOC
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Frozen 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (98%), Xenopus laevis (83%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol, 1% BSA
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Aldolase C Antibody

  • ALDC
  • aldolase 3
  • aldolase C, fructose-bisphosphate
  • Brain-type aldolase
  • EC 4.1.2.13
  • fructoaldolase C
  • fructose-1,6-biphosphate triosephosphate lyase
  • fructose-bisphosphate aldolase C

Background

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Blogs on Aldolase C.

RNA-binding protein Staufen1 conspires with Atxn2 in stress granules to cause neurodegeneration by dysregulating RNA metabolism
By Jamshed Arslan Pharm.D. Spinocerebellar ataxia type 2 (SCA2) is a movement disorder characterized by neurodegeneration. The cause of this autosomal dominant disease is a mutation in the RNA processing gene Atxn2,...  Read full blog post.

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Bioinformatics

Gene Symbol ALDOC
Uniprot