Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-90255

• Activin RIA/ALK-2/Activin Receptor Type 1 Antibodies
• Activin RIA/ALK-2/Activin Receptor Type 1 ELISA Kits
• Activin RIA/ALK-2/Activin Receptor Type 1 Lysates
• Activin RIA/ALK-2/Activin Receptor Type 1 Proteins
• Activin RIA/ALK-2/Activin Receptor Type 1 Proteins and Enzymes