Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2C1E8) - BSA Free Summary
| Immunogen |
Purified recombinant fragment of human Activin RIA/ALK-2/Activin Receptor Type 1 (AA: 21-120) expressed in E. Coli. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
ACVR1 |
| Purity |
Protein G purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:10000
- Flow Cytometry 1:200-1:400
- Western Blot 1:500-1:2000
|
| Theoretical MW |
57.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
PBS |
| Preservative |
0.05% Sodium Azide |
| Concentration |
1 mg/ml |
| Purity |
Protein G purified |
Alternate Names for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (2C1E8) - BSA Free
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.;
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP2-61798) (0)
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Product General Protocols
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Video Protocols
FAQs for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NBP2-61798) (0)
Secondary Antibodies
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Isotype Controls
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