Actin (Muscle Specific) Antibody (HHF35) [mFluor Violet 450 SE]

SDS extract of human myocardium.

Cytoplasmic

Muscle Cell Marker

This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

IgG1 Kappa

Monoclonal

Mouse

ACTA1

Protein A or G purified

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Optimal dilution of this antibody should be experimentally determined.