Novus Biologicals products are now on bio-techne.com

ACMSD Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: ACMSD Antibody [NBP1-86108] - Analysis in human kidney and cerebral cortex tissues. Corresponding ACMSD RNA-seq data are presented for the same tissues.
Western Blot: ACMSD Antibody [NBP1-86108] - Analysis in human liver tissue.
Immunohistochemistry-Paraffin: ACMSD Antibody [NBP1-86108] - Staining of human liver shows weak to moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: ACMSD Antibody [NBP1-86108] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: ACMSD Antibody [NBP1-86108] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: ACMSD Antibody [NBP1-86108] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

ACMSD Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNAL
Predicted Species
Mouse (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ACMSD
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200-1:500
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
ACMSD Recombinant Protein Antigen (NBP1-86108PEP)

Reactivity Notes

Rat (87%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ACMSD Antibody

  • aminocarboxymuconate semialdehyde decarboxylase
  • EC 4.1.1.45,2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
  • Picolinate carboxylase

Background

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-81838
Species: Hu, Mu
Applications: IHC, IHC-P, WB
H00006999-B01P
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NBP2-02860
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
AF4887
Species: Hu
Applications: IP, WB
NB300-537
Species: Bv, Hu, Mu, Rb, Rt
Applications: ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP, KD, WB
MAB1417
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
NBP2-49671
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP1-87243
Species: Hu
Applications: ICC/IF, IHC, IHC-P, IP, WB
NBP1-88370
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
AF4736
Species: Hu
Applications: WB
NBP2-25162
Species: Bv, Eq, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, PLA, WB
DDX0191P-100
Species: Ca, Fe, Hu, Mu, Sh
Applications: ICC/IF, IHC, IHC-P
NBP1-81254
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
NB300-268
Species: Bv, Ce, Hu, I, Mu, Pl
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KO, WB
NBP3-12546
Species: Hu
Applications: IHC-P, IP, WB
NBP1-48021
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
NBP2-32398
Species: Hu
Applications: IHC, IHC-P
NBP2-93989
Species: Hu, Mu, Rt
Applications: ICC/IF, WB
NB300-206
Species: Ba, Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
NBP1-77361
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB

Publications for ACMSD Antibody (NBP1-86108) (0)

There are no publications for ACMSD Antibody (NBP1-86108).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for ACMSD Antibody (NBP1-86108) (0)

There are no reviews for ACMSD Antibody (NBP1-86108). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for ACMSD Antibody (NBP1-86108) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our ACMSD Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol ACMSD
Entrez
Uniprot