HIP1 Related Antibody (1E1)

Closely related to the clathrin-mediated endocytosis regulator HIP1, HIP1R is important in cytoskeletal and membrane traffic. HIP1R prolongs the half-life of growth factor receptors, and helps maintain diversity of adult tissues. This functionality seems to only be relevant in mature systems; whereas, in early development from embryo to juvenile stages, HIP1R does not seem to be critical unless other related proteins are affected. In the absence of HIP1R, growth and differentiation seems to occur without any major effects; however, when both HIP1R and HIP1 are deleted, kypholordosis and dwarfism occurs. This seems to indicate that HIP1 and HIP1R share similar roles in vivo, and can mostly compensate for the absence of each other.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Bacteria.

We have publications tested in 3 applications: IF/IHC, IP, WB.

Showing Publications 1 - 4 of 4.

Publications using NB300-206	Applications	Species
Kellner M, Rohrmoser M, Forne I et al. DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex Exp. Cell Res. 2015-03-28 [PMID: 25825154] (IP, WB, Human)	IP, WB	Human
Mills IG et al. Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors. J Cell Biol; 70: 191-200. 2005-01-01 [PMID: 16027218] (WB, Bacteria)	WB	Bacteria
Hyun TS, Li L, Oravecz-Wilson KI, Bradley SV, Provot MM, Munaco AJ, Mizukami IF, Sun H, Ross TS. Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Mol Cell Biol;24(10):4329-40. 2004-05-01 [PMID: 15121852] (WB, IF/IHC, Human, Mouse)	WB, IF/IHC	Human, Mouse
Hyun TS, Rao DS, Saint-Dic D, Michael LE, Kumar PD, Bradley SV, Mizukami IF, Oravecz-Wilson KI, Ross TS. HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains. J Biol Chem;279(14):14294-306. 2004-04-02 [PMID: 14732715] (WB, IP, Human)	WB, IP	Human

Array NB300-206

• HIP1 Related Antibodies
• HIP1 Related Lysate
• HIP1 Related Proteins