ABCB5 Antibody - BSA Free

The ATP-binding cassette sub-family B member 5 (ABCB5) is an ABC transporter and PGP member. It is highly expressed in skin and in malignant melanoma. When two abnormal growths of tissues occur, resulting in multiple malignancies, ABCB5 is often highly expressed. This elevated expression in tumor cells can indicate a propensity towards therapeutic failure in many cases. Analysis of ABCB5 concentrations in tumors has been suggested as a fairly dependable qualitative biomarker for assessing the malignancy of melanomas.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 6 of 6.

Publications using NBP1-77687	Applications	Species
Lasagni Vitar R, Triani F, Barbariga M et al. Substance P/neurokinin-1 receptor pathway blockade ameliorates limbal stem cell deficiency by modulating mTOR pathway and preventing cell senescence Stem cell reports 2022-03-10 [PMID: 35334220]
Tucci M, D'Oronzo S, Mannavola F et al. Dual-procedural separation of CTCs in cutaneous melanoma provides useful information for both molecular diagnosis and prognosis Ther Adv Med Oncol 2020-03-13 [PMID: 32206092] (Human)		Human
Ksander BR, Kolovou PE, Wilson BJ et al. ABCB5 is a limbal stem cell gene required for corneal development and repair. Nature 2014-07-17 [PMID: 25030174] (WB)	WB
Lee J, Abdeen A, Li Y et al. Gradient and Dynamic Hydrogel Materials to Probe Dynamics in Cancer Stem Cell Phenotypes ACS Applied Bio Materials 2020-12-16
Strobel SB, Machiraju D, HUlsmeyer I et al. Expression of Potential Targets for Cell-Based Therapies on Melanoma Cells Life (Basel, Switzerland) 2021-03-24 [PMID: 33805080] (IF/IHC, Human)	IF/IHC	Human
Roy T, Boateng ST, Banang-Mbeumi S et al. Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers Bioorganic chemistry 2021-02-01 [PMID: 33450548]

Array NBP1-77687

• ABCB5 Antibodies
• ABCB5 Protein