Novus Biologicals products are now on bio-techne.com

5-HT4 Antibody

Images

 
Immunohistochemistry-Paraffin: 5-HT4 Antibody [NBP3-14526] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain vessel after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Po, Bt, Ca, Eq, Pm, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

5-HT4 Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 20 amino acid peptide from C-Terminus of human 5HT4.
Epitope
C-Terminus
Specificity
Human 5-HT4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Porcine (100%), Bat (90%), Canine (95%), Equine (100%), Primate (100%), Monkey (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
HTR4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Reactivity Notes

Expected reactivity based on percent sequence identity: Guinea pig (85%), Mouse, Rat (80%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for 5-HT4 Antibody

  • 5HT4
  • 5-HT4
  • 5-HT-4
  • 5-HT4R
  • 5-hydroxytryptamine (serotonin) receptor 4,5-hydroxytryptamine receptor 4,5-HT45-hydroxytryptamine4 receptor
  • cardiac 5-HT4 receptor
  • HTR4
  • Serotonin receptor 4

Background

The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). A ninth isoform (5-HT4H) results in the insertion of 14 amino acids into the second intracellular loop. 5-HT4 receptor expression has been documented primarily in the brain, and in colon, heart, and vessel. An EST has been isolated from a human cancerous nerve library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-26091
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
NBP2-21590
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC-Fr, Simple Western, WB
NB300-731
Species: Gp, Hu, Mu, Rb, Rt, Sh, Ye
Applications: B/N, ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP, WB
NBP2-16684
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NB100-56352
Species: Ca, Hu, Mu, Rt
Applications: Flow, ICC/IF, Simple Western, WB
NB100-56350
Species: Hu, Mu, Rt
Applications: WB
MAB5764
Species: Hu
Applications: CyTOF-ready, Flow, IHC
NBP1-46557
Species: Mu, Rt
Applications: IHC, WB
NBP1-90322
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP1-88191
Species: Hu, Mu
Applications: IHC, IHC-P, WB
MAB4375
Species: Hu, Mu, Rt
Applications: IHC
NLS590
Species: Hu, Pm
Applications: IHC, IHC-P
H00002770-M01
Species: Hu
Applications: ELISA, IHC, IHC-P, S-ELISA, WB
NB100-1533
Species: Hu, Mu, Po, Rt, Sh
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
H00006532-D01P
Species: Hu, Mu
Applications: WB
NBP1-00178
Species: Hu, Mu, Sh
Applications: Flow, ICC/IF, IHC, IHC-Fr, PEP-ELISA, WB
AF4928
Species: Hu
Applications: CyTOF-ready, Flow, WB
NBP3-14526
Species: Hu, Po, Bt, Ca, Eq, Pm, Pm
Applications: IHC

Publications for 5-HT4 Antibody (NBP3-14526) (0)

There are no publications for 5-HT4 Antibody (NBP3-14526).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for 5-HT4 Antibody (NBP3-14526) (0)

There are no reviews for 5-HT4 Antibody (NBP3-14526). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for 5-HT4 Antibody (NBP3-14526) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our 5-HT4 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol HTR4